{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T01:27:17Z","timestamp":1788398837656,"version":"build-2803163510"},"reference-count":7,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T00:00:00Z","timestamp":1745366400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,5]]},"abstract":"ABSTRACT<\/jats:title>\n Musicogenic epilepsy (ME) is a rare form of reflex epilepsy with a prevalence of 1 in 10,000,000. Recent research suggests a potential link between ME and autoimmune encephalitis, particularly involving glutamic acid decarboxylase 65\u2010isoform (GAD65) antibodies. A 48\u2010year\u2010old female presented with a one\u2010year history of music\u2010triggered seizures. Her episodes were characterized by an initial aura followed by unresponsiveness and oral automatisms. Electroencephalography revealed abnormalities in the left anterior temporal lobe and temporal leads. Laboratory studies showed positive anti\u2010GAD65 antibodies. The patient was treated with a combination of antiepileptic medication (Lamotrigine) and corticosteroids and intravenous immunoglobulin. This case contributes to the growing evidence supporting an association between ME and autoimmune mechanisms, particularly GAD65 antibody\u2010mediated autoimmunity. It highlights the importance of screening autoimmune factors in ME patients and highlights the need for further research into targeted treatment strategies.<\/jats:p>","DOI":"10.1002\/ccr3.70444","type":"journal-article","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:26:20Z","timestamp":1745454380000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Autoimmune Encephalitis and Musicogenic Epilepsy: A Case of\n GAD65<\/scp>\n Antibody\u2010Associated Seizure"],"prefix":"10.1002","volume":"13","author":[{"given":"Ali","family":"Mohammadi\u2010Asl","sequence":"first","affiliation":[{"name":"Iranian Center of Neurological Research, Neuroscience Institute Tehran University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1275-1138","authenticated-orcid":false,"given":"Amir Reza","family":"Bahadori","sequence":"additional","affiliation":[{"name":"Iranian Center of Neurological Research, Neuroscience Institute Tehran University of Medical Sciences Tehran Iran"},{"name":"School of Medicine Shiraz University of Medical Sciences Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iman","family":"Sabzgolin","sequence":"additional","affiliation":[{"name":"Iranian Center of Neurological Research, Neuroscience Institute Tehran University of Medical Sciences Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afshan","family":"Davari","sequence":"additional","affiliation":[{"name":"Iranian Center of Neurological Research, Neuroscience Institute Tehran University of Medical Sciences Tehran Iran"},{"name":"Medical Colleges Tehran University of Medical Sciences Tehran 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Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8138-1172","authenticated-orcid":false,"given":"Sara","family":"Ranji","sequence":"additional","affiliation":[{"name":"Iranian Center of Neurological Research, Neuroscience Institute Tehran University of Medical Sciences Tehran 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