{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T23:37:55Z","timestamp":1771457875559,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T00:00:00Z","timestamp":1744761600000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Plummer\u2010Vinson Syndrome (PVS) is a rare disorder characterized by the triad of dysphagia, iron\u2010deficiency anemia, and esophageal webs. Limited data on its prevalence exist, with most information derived from case reports. We present the case of a 60\u2010year\u2010old woman with a 6\u2010month history of a progressively enlarging anterior neck mass and worsening symptoms of heart failure, heat intolerance, and dysphagia. Diagnostic evaluation revealed a multinodular goiter, microcytic hypochromic anemia, hyperthyroidism, hypokalemia, and esophageal webs. She was diagnosed with PVS in conjunction with thyro\u2010cardiac disease and acute decompensated heart failure. Treatment included iron supplementation, pneumatic dilation, and management of her thyroid and cardiac conditions, resulting in significant clinical improvement. This case demonstrates the importance of early recognition and treatment of PVS to prevent complications and reduce morbidity.<\/jats:p>","DOI":"10.1002\/ccr3.70447","type":"journal-article","created":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T00:55:22Z","timestamp":1744851322000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Plummer\u2010Vinson Syndrome With Coexistent Thyro\u2010Cardiac Disease and Acute Decompensated Heart Failure: A Case Report"],"prefix":"10.1002","volume":"13","author":[{"given":"Suleiman","family":"Ayalew","sequence":"first","affiliation":[{"name":"School of Medicine, College of Medicine and Health Sciences University of Gondar  Gondar Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9095-5668","authenticated-orcid":false,"given":"Michael A.","family":"Negussie","sequence":"additional","affiliation":[{"name":"School of Medicine, College of Health Sciences Addis Ababa University  Addis Ababa Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tinsae","family":"Anebo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Thomas Jefferson University\u2014Sidney Kimmel Medical College  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fitsum A.","family":"Gemechu","sequence":"additional","affiliation":[{"name":"School of Medicine, College of Health Sciences Addis Ababa University  Addis Ababa Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yishak","family":"Abdulsemed","sequence":"additional","affiliation":[{"name":"School of Medicine, College of Medicine and Health Sciences University of Gondar  Gondar Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Segenet B.","family":"Mengistu","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine College of Medicine and Health Sciences, University of Gondar  Gondar Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,16]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750\u20101172\u20101\u201036"},{"issue":"5","key":"e_1_2_11_3_1","first-page":"402","article-title":"Plummer\u2010Vinson syndrome","volume":"85","author":"Ben Gamra O.","year":"2007","journal-title":"La Tunisie M\u00e9dicale"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.678326"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1442\u20102050.2003.00316.x"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005176\u2010200201000\u201000021"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572\u20100241.2003.07425.x"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20102007\u20101005446"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004836\u2010199910000\u201000016"},{"issue":"2","key":"e_1_2_11_10_1","article-title":"Plummer\u2010Vinson Syndrome: A Case Report and Literature Review","volume":"5","author":"Lawoyin D. O.","year":"2006","journal-title":"Internet Journal of Dental Science"},{"key":"e_1_2_11_11_1","first-page":"836","volume-title":"Clinical Physiology of Acid\u2010Base and Electrolyte Disorders","author":"Rose B. D.","year":"2001"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.70447","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T14:54:46Z","timestamp":1764255286000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.70447"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1002\/ccr3.70447"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.70447","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"2024-09-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70447"}}