{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T14:59:07Z","timestamp":1764255547167,"version":"3.46.0"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T00:00:00Z","timestamp":1745280000000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Neuroblastoma (NB) is a rare solid tumor of the sympathetic nervous system, primarily occurring in children and rarely in adults. Its extracranial origin stems from the medullary region of the adrenal gland or sympathetic ganglia. We report an 18\u2010year\u2010old female who presented with a 6\u2010month history of abdominal swelling and tenderness. Imaging revealed a large retroperitoneal mass causing significant displacement of adjacent structures. Following multidisciplinary optimization, a huge tumor was successfully resected surgically. Histopathology confirmed the diagnosis of adrenal NB. The patient underwent adjuvant chemotherapy and remained symptom\u2010free with favorable outcomes during a 9\u2010month follow\u2010up. This case underscores the importance of comprehensive diagnostic evaluation and multimodal management in treating rare adult adrenal NB.<\/jats:p>","DOI":"10.1002\/ccr3.70453","type":"journal-article","created":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T07:00:57Z","timestamp":1745305257000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Giant Adrenal Neuroblastoma in Adults: Surgical Management and Comprehensive Review"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-1634-7226","authenticated-orcid":false,"given":"Charles John","family":"Nhungo","sequence":"first","affiliation":[{"name":"Department of Surgery, School of Medicine Muhimbili University of Health and Allied Sciences  Dar es Salaam Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doreen Gerion","family":"Gilbert","sequence":"additional","affiliation":[{"name":"Department of Pathology, School of Medicine Muhimbili University of Health and Allied Sciences  Dar es Salaam Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boniface","family":"Nzowa","sequence":"additional","affiliation":[{"name":"Department of Surgery, School of Medicine Muhimbili University of Health and Allied Sciences  Dar es Salaam Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipo","family":"Felix","sequence":"additional","affiliation":[{"name":"Department of Surgery, School of Medicine Muhimbili University of Health and Allied Sciences  Dar es Salaam Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nimwindael","family":"Msangi","sequence":"additional","affiliation":[{"name":"Department of Radiology Muhimbili National Hospital  Dar es Salaam Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theoflo","family":"Mmbando","sequence":"additional","affiliation":[{"name":"Department of Urology Muhimbili National Hospital  Dar es Salaam Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel","family":"Mtaturu","sequence":"additional","affiliation":[{"name":"Department of Urology Muhimbili National Hospital  Dar es Salaam Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Obadia","family":"Nyongole","sequence":"additional","affiliation":[{"name":"Department of Surgery, School of Medicine Muhimbili University of Health and Allied Sciences  Dar es Salaam Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles A.","family":"Mkony","sequence":"additional","affiliation":[{"name":"Department of Surgery, School of Medicine Muhimbili University of Health and Allied Sciences  Dar es Salaam Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,22]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)60983-0"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/2162-3619-3-20"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.31399"},{"issue":"1","key":"e_1_2_14_5_1","first-page":"1","article-title":"Adrenal Neuroblastoma: A Rare Entity in Adulthood","volume":"2","author":"Majumder S. 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