{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:29:50Z","timestamp":1789691390584,"version":"4.0.1"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T00:00:00Z","timestamp":1745193600000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Vagus schwannomas are rare, benign masses that arise in the cervical region but can develop anywhere along the Vagus nerve. In most cases, patients present in their third to sixth decades, with neck swelling and hoarseness; herein, we discuss a case report of a 41\u2010year\u2010old female who presented with slurred speech and locking of her tongue and was diagnosed with Vagus schwannoma. The patient had an inability to speak properly and locking of her tongue during speech, with pain to the right side of the neck as Intermittent, prompted by turning her head to the right and shooting pain to her shoulder, which is short\u2010lived, with a sensation of difficulty swallowing and talking that is alleviated by moving her head to a neutral position. On examination, there was mild neck stiffness, fasciculations of the tongue, and left deviation of the tongue with inability to swallow. Blood pressure was 128\/70\u2009mmHg with 42\u2009bpm bradycardia, which was persistent on several readings, with a small right neck mass measuring 1\u2009cm\u2009\u00d7\u20092\u2009cm, non\u2010tender on palpation. Imaging studies showed a well\u2010defined ovoid lesion centered in the right retrostyloid parapharyngeal space measuring 3.3\u2009\u00d7\u20092.1\u2009\u00d7\u20093.8\u2009cm with central T2 hyperintensities representing a nerve sheath tumor that appears stable in size and morphology. The histology report typically displayed a characteristic pattern with two distinct tissue types, Antoni A and Antoni B, with tightly packed spindle cells arranged in palisades around a central verocay body and a looser arrangement of myxoid matrix. Immunohistochemistry showed lesional cells had strong immunopositivity for S100 and were negative for CD34. Hence, the conclusion of a Vagus nerve schwannoma. Patient was sent to the radiation oncology team and was started on Cyberknife 25\u2009Gy treatment in five fractions, which were completed and sent for re\u2010evaluation and follow\u2010up. There was no surgical intervention in this case due to the delicate anatomical location of the mass; hence, Cyberknife radiation was the best option for treatment. Vagus schwannomas are rare, benign masses that usually develop in the cervical region but can arise anywhere along the Vagus nerve. Patients may be asymptomatic, but in most cases, they present in their third to sixth decades; hence, they should be considered in patients with otherwise unexplained bradycardia, with a history of dysphagia, slurred speech, and cervical masses.<\/jats:p>","DOI":"10.1002\/ccr3.70469","type":"journal-article","created":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T02:10:30Z","timestamp":1745287830000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Vagus Nerve Schwannoma: A Case Report and Literature Review"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9532-9807","authenticated-orcid":false,"given":"Kato","family":"Ronald","sequence":"first","affiliation":[{"name":"Gulu University Faculty of Medicine, Kampala Uganda  Gulu Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kantu","family":"Ronald","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Health Sciences Makerere University  Kampala Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacinta","family":"Ambaru","sequence":"additional","affiliation":[{"name":"Department of Oncology Uganda Cancer Institute  Kampala Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Sekiwunga","sequence":"additional","affiliation":[{"name":"Department of Radiology, Faculty of Health Sciences Makerere University  Kampala Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405\u2010011\u20101491\u20104"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2007.01.006"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1516\u201031802007000400005"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12070\u2010011\u20100154\u20105"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.wco.0000044763.39452.aa"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjorl.2021.05.013"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004050000242"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.21898"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12070\u2010015\u20100925\u20105"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.133.7.662"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1985.00800130085011"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2016.0113"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.15537\/smj.2015.11.12314"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.47102\/annals-acadmedsg.V36N4p233"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405\u2010013\u20102520\u20102"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/lio2.122"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/7603814"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.70469","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T14:54:21Z","timestamp":1764255261000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.70469"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1002\/ccr3.70469"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.70469","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"2025-01-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70469"}}