{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T03:36:36Z","timestamp":1783740996562,"version":"3.55.0"},"reference-count":20,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T00:00:00Z","timestamp":1751846400000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Actinic granuloma (AG), a rare and idiopathic skin condition primarily affecting middle\u2010aged and elderly individuals, is known for its persistent, asymptomatic annular plaques appearing on sun\u2010exposed areas. This report details the case of a 48\u2010year\u2010old diabetic male farmer with a rare presentation of generalized AG. The patient's lesions were unusually widespread, affecting sun\u2010exposed sites, and failed to respond adequately to tofacitinib therapy.<\/jats:p>","DOI":"10.1002\/ccr3.70618","type":"journal-article","created":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T02:38:35Z","timestamp":1751942315000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A Case Report of Generalization of Localized Actinic Granuloma, an Unusual Diffuse Presentation Not Responding to Tofacitinib"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-7324-0347","authenticated-orcid":false,"given":"Saman","family":"Al\u2010Zahawi","sequence":"first","affiliation":[{"name":"Department of Dermatology, Razi Hospital Tehran University of Medical Sciences (TUMS)  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alireza","family":"Ghanadan","sequence":"additional","affiliation":[{"name":"Department of Dermatopathology, Razi Hospital Tehran University of Medical Sciences (TUMS)  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Saberi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Razi Hospital Tehran University of Medical Sciences (TUMS)  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,7]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.5826\/dpc.040a04"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.5070\/D31910020019"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.160493"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0365-05962011000200019"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000000841"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.13502"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2019-231580"},{"key":"e_1_2_11_9_1","first-page":"589","volume-title":"Annales de Dermatologie et de V\u00e9n\u00e9r\u00e9ologie","author":"Margerin F.","year":"2017"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2013.01.071"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S422554"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdcr.2016.05.021"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2015.03.002"},{"key":"e_1_2_11_14_1","volume-title":"Dermatology e\u2010Book","author":"Bolognia J. L.","year":"2012"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijwd.2015.06.001"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2015.27.2.214"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000001227"},{"issue":"7","key":"e_1_2_11_18_1","first-page":"699","article-title":"Treatment of Annular Elastolytic Giant Cell Granuloma With Topical Tretinoin","volume":"16","author":"Wagenseller A.","year":"2017","journal-title":"Journal of Drugs in Dermatology"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdcr.2020.08.034"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.05.098"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.25259\/IJDVL_554_2024"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.70618","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T04:19:11Z","timestamp":1763698751000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.70618"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":20,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1002\/ccr3.70618"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.70618","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"2025-02-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70618"}}