{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T08:45:02Z","timestamp":1784018702455,"version":"3.55.0"},"reference-count":17,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,7,11]],"date-time":"2025-07-11T00:00:00Z","timestamp":1752192000000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Syphilis is a sexually transmitted infection caused by the spirochete bacterium\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Treponema pallidum<\/jats:italic>\n                    <\/jats:styled-content>\n                    , presenting with oral manifestations at various stages of the disease, including primary, secondary, and tertiary phases. Oral manifestations tend to be misdiagnosed as other lesions; therefore, the diagnosis and treatment may be delayed. This case reports the diagnosis and treatment of a 27\u2010year\u2010old female patient who presented to the Oral Medicine clinic with oral syphilis, emphasizing the clinical presentation before and after treatment.\n                  <\/jats:p>","DOI":"10.1002\/ccr3.70620","type":"journal-article","created":{"date-parts":[[2025,7,12]],"date-time":"2025-07-12T05:20:12Z","timestamp":1752297612000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A Case Report of Oral Syphilis Before and After Management"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0601-6452","authenticated-orcid":false,"given":"Abdulhameed","family":"Alsarraf","sequence":"first","affiliation":[{"name":"Oral Medicine Clinic, Jahra Dental Speciality Center Ministry of Health  Jahra Medical City Kuwait"},{"name":"Oral Medicine &amp; Pathology Clinic, Dental Department Kuwait Oil Company Hospital  AlAhmadi City Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aisha","family":"Almudahkah","sequence":"additional","affiliation":[{"name":"Dental Administration Ministry of Health  Kuwait City Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Alabdalrazaq","sequence":"additional","affiliation":[{"name":"Dental Administration Ministry of Health  Kuwait City Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qutaibah","family":"Alfadalah","sequence":"additional","affiliation":[{"name":"Dental Administration Ministry of Health  Kuwait City Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,11]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-009-0127-0"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1901593"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp048126"},{"key":"e_1_2_10_5_1","unstructured":"World Health Organization [WHO] \u201cSyphilis \u201d (2024) https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/syphilis#:~:text=Most%20infections%20are%20asymptomatic%20or cases%20with%20adverse%20birth%20outcomes."},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.12.2.187"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.1903"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-114-12-1005"},{"issue":"1","key":"e_1_2_10_9_1","first-page":"87","article-title":"Sexually Transmitted Diseases, Unintended Pregnancy, and Adolescent Health Promotion","volume":"10","author":"Santelli J. S.","year":"1999","journal-title":"Adolescent Medicine (Philadelphia)"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.6.2051"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1128\/iai.60.3.1076-1083.1992"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1286-4579(02)01638-6"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00070-13"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)32411-4"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2018.10.023"},{"issue":"12","key":"e_1_2_10_16_1","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1111\/j.1610-0387.2006.06072.x","article-title":"Diagnosis of Syphilis: Clinical and Laboratory Problems","volume":"4","author":"Lautenschlager S.","year":"2006","journal-title":"JDDG: Journal of the German Society of Dermatology"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-020-01283-4"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa176"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.70620","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T04:18:45Z","timestamp":1763698725000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.70620"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":17,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1002\/ccr3.70620"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.70620","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"2025-04-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70620"}}