{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T16:55:45Z","timestamp":1757609745500,"version":"3.44.0"},"reference-count":19,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,7,27]],"date-time":"2025-07-27T00:00:00Z","timestamp":1753574400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Brodie's abscess, a subacute form of osteomyelitis, is characterized by localized symptoms and can be challenging to diagnose due to its nonspecific clinical presentation. We report a rare case of distal femoral Brodie's abscess in a healthy child, emphasizing the diagnostic intricacies and management. A 15\u2010year\u2010old previously healthy patient presented with chronic left knee pain of insidious onset and progressive nature. Conservative measures were initially employed, leading to transient symptom resolution. Clinical examination revealed limited flexion, and imaging demonstrated a well\u2010corticated osteolytic lesion with a sclerotic rim on the distal femur, along with the characteristic \u201cpenumbra sign\u201d on magnetic resonance imaging (MRI). Brodie's abscess can mimic benign conditions, leading to delayed diagnosis. Clinicians should maintain vigilance when evaluating patients with unexplained joint pain, especially in the absence of systemic symptoms. Early recognition and appropriate management, as exemplified in this case, are crucial for preventing complications and ensuring a favorable outcome. This report contributes to the understanding of this rare condition and highlights the significance of timely intervention in Brodie's abscess cases.<\/jats:p>","DOI":"10.1002\/ccr3.70644","type":"journal-article","created":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T03:53:59Z","timestamp":1753674839000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Rare Cause of Recurrent Left Knee Pain in an Adolescent Male: A Case Report of Distal Femoral Brodie's Abscess"],"prefix":"10.1002","volume":"13","author":[{"given":"Adeel Ahmed","family":"Siddiqui","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery Dow University of Health Sciences  Karachi Sindh Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4002-8684","authenticated-orcid":false,"given":"Muhammad Waqas","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Dow University of Health Sciences  Karachi Sindh Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sajjad","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Dow University of Health Sciences  Karachi Sindh Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taimoor","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Dow University of Health Sciences  Karachi Sindh Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asif","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Dow University of Health Sciences  Karachi Sindh Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8032-7462","authenticated-orcid":false,"given":"Hussain Haider","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Dow University of Health Sciences  Karachi Sindh Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7935-7333","authenticated-orcid":false,"given":"Tirth","family":"Dave","sequence":"additional","affiliation":[{"name":"Bukovinian State Medical University  Chernivtsi Ukraine"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,7,27]]},"reference":[{"issue":"3","key":"e_1_2_13_2_1","first-page":"E53","article-title":"Infection of the Appendicular Skeleton","volume":"14","author":"Bohndorf K.","year":"2004","journal-title":"European Radiology"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina57060544"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.7150\/jbji.31843"},{"issue":"7","key":"e_1_2_13_5_1","article-title":"Brodie's Abscess: A Diagnostic Conundrum","volume":"13","author":"Salik M.","year":"2021","journal-title":"Cureus"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.13107\/jocr.2021.v11.i09.2406"},{"issue":"6","key":"e_1_2_13_7_1","first-page":"436","article-title":"Treatment of Brodie's Abscess: Excellent Results From Curettage, Bone Grafting and Antibiotics","volume":"52","author":"Olasinde A. 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B.","year":"2021","journal-title":"Journal of the American Academy of Orthopaedic Surgeons Global Research & Reviews"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.5152\/j.aott.2020.03.33"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.70644","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T11:12:41Z","timestamp":1756897961000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.70644"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,27]]},"references-count":19,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["10.1002\/ccr3.70644"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.70644","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2025,7,27]]},"assertion":[{"value":"2023-09-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70644"}}