{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T16:56:39Z","timestamp":1757609799137,"version":"3.44.0"},"reference-count":13,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T00:00:00Z","timestamp":1753833600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>In areas where hydatid disease is endemic, hydatid cyst embolism should be recognized as a rare but important differential diagnosis in young patients presenting with stroke. Awareness of this potential etiology is essential for early detection, timely intervention, and prevention of severe neurological complications. Cardiac hydatid cysts are infrequent, representing 0.5%\u20132% of all hydatid disease cases. The left ventricular wall is the most common location for cardiac disease, while interventricular septum involvement is much rarer. Echocardiography is favorable as a non\u2010invasive diagnostic tool with high sensitivity and low cost. Surgical removal with open heart surgery is the treatment of choice for such cysts. Here, we report a case of a hydatid cyst in a 17\u2010year\u2010old patient in the interventricular septum complicated with cerebral embolization. A 17\u2010year\u2010old male presented with a month\u2010long history of right\u2010sided muscle weakness and slurred speech. Neurological examination revealed weak motor power (3\/5) in the right upper and lower extremities with hypertonia, hyperreflexia, Babinski sign, and expressive aphasia. Brain MRI showed multiple lesions, including an irregularly shaped area in the left frontal lobe and two lesions in the left occipital\u2010parietal region. A CT neck of the neck, chest, abdomen, and pelvis (NCAP) showed the presence of a cystic heterogeneous formation located at the level of the cardiac interventricular septum. Our decision was surgical removal of the cyst with open\u2010heart surgery. The cystic germinal layer was completely resected, and the cavity was marsupialized. The case reported here is of particular interest not only because a hydatid cyst is located in the interventricular septum but also because the giant hydatid cyst was detected by neurological symptoms without any previously noted cardiac manifestations. Embolism of hydatid cysts should be considered in the differential diagnosis of stroke in young patients, especially in endemic areas.<\/jats:p>","DOI":"10.1002\/ccr3.70687","type":"journal-article","created":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T06:15:15Z","timestamp":1753942515000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Primary Isolated Interventricular Hydatid Cyst With Left Ventricular Vegetation Presents With Neurological Manifestations: A Case Report"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4483-0893","authenticated-orcid":false,"given":"Albaraa","family":"Bara","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery Damascus University Cardiovascular Surgical Center  Damascus Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7158-1127","authenticated-orcid":false,"given":"Sabah","family":"Refaieh","sequence":"additional","affiliation":[{"name":"Endocrinology Resident, Department of Internal Medicine Damascus University  Damascus Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia","family":"Batha","sequence":"additional","affiliation":[{"name":"Internal Medicine Resident, Department of Internal Medicine Damascus University  Damascus Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meree","family":"Daoud","sequence":"additional","affiliation":[{"name":"Cardiology Resident, Department of Cardiology Damascus University  Damascus Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adeeb","family":"Makhlouf","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Alassad University Hospital Damascus University  Damascus Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,7,30]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.4103\/0971\u20104065.120347"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.35410"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.15171\/jcvtr.2019.13"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0003319717690093"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2004.04.031"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2005.10.015"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2017.11.013"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/021849230601400324"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2019.09.004"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.25.4.886"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/pl00021006"},{"issue":"1","key":"e_1_2_11_13_1","first-page":"120","article-title":"Stroke: A Rare Presentation of Cardiac Hydatidosis","volume":"51","author":"Singh N. P.","year":"2003","journal-title":"Neurology India"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0003\u20104975(99)00692\u2010x"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.70687","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T11:11:19Z","timestamp":1756897879000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.70687"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,30]]},"references-count":13,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["10.1002\/ccr3.70687"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.70687","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2025,7,30]]},"assertion":[{"value":"2024-10-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70687"}}