{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T16:56:47Z","timestamp":1757609807811,"version":"3.44.0"},"reference-count":3,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:00:00Z","timestamp":1755129600000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>A 42\u2010year\u2010old woman with a C677T mutation in the methylenetetrahydrofolate reductase gene and a history of transient ischemic attack underwent transcatheter closure of an ostium secundum atrial septal defect (ASD\u2010OS) using a Figulla Flex II device. Two years later, she presented with an ischemic stroke. Imaging revealed late embolization of the occluder device to the aorto\u2010iliac bifurcation. As she remained asymptomatic, a conservative approach was adopted. A second transcatheter ASD\u2010OS closure was successfully performed. This case underscores the potential contribution of inherited thrombophilia to recurrent embolic events, the importance of long\u2010term surveillance for device complications, and the value of multimodal imaging in guiding clinical decision making.<\/jats:p>","DOI":"10.1002\/ccr3.70718","type":"journal-article","created":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T06:33:27Z","timestamp":1755239607000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Unexpected Stroke Two Years After Atrial Septal Defect Closure: A Case of Late Device Embolization"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3303-5640","authenticated-orcid":false,"given":"Nuria","family":"Pueyo\u2010Balsells","sequence":"first","affiliation":[{"name":"Department of Cardiology Arnau de Vilanova University Hospital  Lleida Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8670-4898","authenticated-orcid":false,"given":"Ignacio","family":"Barriuso","sequence":"additional","affiliation":[{"name":"University Hospital San Agustin  Avil\u00e9s Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6200-2472","authenticated-orcid":false,"given":"Marta","family":"Zielonka","sequence":"additional","affiliation":[{"name":"Department of Cardiology Arnau de Vilanova University Hospital  Lleida Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7129-1923","authenticated-orcid":false,"given":"Carlos","family":"Izurieta","sequence":"additional","affiliation":[{"name":"Department of Cardiology Arnau de Vilanova University Hospital  Lleida Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6598-3576","authenticated-orcid":false,"given":"Kristian","family":"Rivera","sequence":"additional","affiliation":[{"name":"Department of Cardiology Arnau de Vilanova University Hospital  Lleida Spain"},{"name":"Grup de Fisiologia i Patologia Card\u00edaca, Institut de Recerca Biom\u00e8dica de Lleida Fundaci\u00f3 Dr. Pifarr\u00e9 IRBLleida  Lleida Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,14]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.33588\/rn.4310.2005542"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carrev.2024.02.014"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2017.04.014"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.70718","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T11:11:35Z","timestamp":1756897895000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.70718"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":3,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["10.1002\/ccr3.70718"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.70718","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"2025-04-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70718"}}