{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:36:17Z","timestamp":1786977377026,"version":"build-2736575974"},"reference-count":27,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T00:00:00Z","timestamp":1758499200000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>This case report describes the successful treatment of a mature anterior tooth with an open apex and chronic apical abscess using a regenerative endodontic procedure. A 36\u2010year\u2010old man with a history of trauma to tooth 11 at age 10 presented with incomplete root development and an asymptomatic chronic apical abscess. Cone beam tomography revealed a periradicular lesion with buccal bone plate loss. After biomechanical preparation using K\u2010type files and irrigation with 1% sodium hypochlorite, calcium hydroxide was placed as intracanal medication for 14\u2009days. Bleeding was induced by overinstrumenting the periapical tissues with a #25\u2009K\u2010file, and a bioceramic material was placed over the blood clot, followed by a composite resin coronal seal. At the 4\u2010year follow\u2010up, the patient was asymptomatic, with complete bone plate formation and no periradicular lesion or root resorption, although no hard tissue formation or changes in root canal morphology were observed.<\/jats:p>","DOI":"10.1002\/ccr3.70911","type":"journal-article","created":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T03:43:14Z","timestamp":1758598994000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Regenerative Endodontic Procedure of a Mature Anterior Tooth With Open Apex and Chronic Apical Abscess: A Case Report With 4\u2010Years Follow\u2010Up"],"prefix":"10.1002","volume":"13","author":[{"given":"Murilo Priori","family":"Alcalde","sequence":"first","affiliation":[{"name":"Department of Dentistry, Endodontics and Dental Materials, Bauru Dental School University of S\u00e3o Paulo  Bauru Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4726-8106","authenticated-orcid":false,"given":"Raimundo Sales","family":"de Oliveira Neto","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Endodontics and Dental Materials, Bauru Dental School University of S\u00e3o Paulo  Bauru Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estela Franzolin Pires","family":"de Almeida","sequence":"additional","affiliation":[{"name":"Department of Dentistry Unisagrado  Bauru Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renan Diego","family":"Furlan","sequence":"additional","affiliation":[{"name":"Department of Dentistry Unisagrado  Bauru Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo Roberto Jara","family":"de Souza","sequence":"additional","affiliation":[{"name":"Department of Dentistry Unisagrado  Bauru Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo Ricci","family":"Vivan","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Endodontics and Dental Materials, Bauru Dental School University of S\u00e3o Paulo  Bauru Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo Andres","family":"Amoroso\u2010Silva","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry Universidade Estadual de Londrina  Londrina Paran\u00e1 Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco Ant\u00f4nio H\u00fangaro","family":"Duarte","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Endodontics and Dental Materials, Bauru Dental School University of S\u00e3o Paulo  Bauru Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guilherme Ferreira","family":"da Silva","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Endodontics and Dental Materials, Bauru Dental School University of S\u00e3o Paulo  Bauru Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,22]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/edt.12979"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2021.03.015"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/app12094212"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2024.02.012"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2011.01.011"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2007.07.018"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2006.09.013"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/5234136"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.22203\/eCM.v037a11"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13300"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2008.08.013"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.adaj.2016.01.009"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sdentj.2024.07.006"},{"key":"e_1_2_14_15_1","unstructured":"Endodontist A \u201cAae Clinical Considerations for a Regenerative Procedure. 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