{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T09:13:07Z","timestamp":1790241187087,"version":"4.1.0"},"reference-count":8,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T00:00:00Z","timestamp":1758672000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T00:00:00Z","timestamp":1758672000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Low phospholipid\u2010associated cholelithiasis (LPAC) syndrome is a rare and underdiagnosed cause of recurrent intrahepatic and extrahepatic bile duct stones. We report the case of a 32\u2010year\u2010old male with a history of laparoscopic cholecystectomy and multiple ERCPs who presented with acute epigastric pain and vomiting. He had recurrent episodes of cholangitis over several months, each managed with ERCP, balloon extraction, and biliary stenting. Imaging revealed biliary dilatation with obstructive stones. Emergency ERCP retrieved a large stone with pus and debris, followed by stent placement and clinical improvement. He was diagnosed with LPAC syndrome and discharged on ursodeoxycholic acid. Follow\u2010up imaging demonstrated persistent but improving biliary dilation without structural anomalies or abscesses. This case underscores the recurrent nature of LPAC syndrome and the importance of considering this diagnosis in young adults with unexplained biliary symptoms post\u2010cholecystectomy. Early recognition and long\u2010term management are essential to reduce recurrence.<\/jats:p>","DOI":"10.1002\/ccr3.70942","type":"journal-article","created":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T12:56:21Z","timestamp":1758718581000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Low Phospholipid\u2010Associated Cholelithiasis Syndrome: A Case Report of Chronic Recurrent Cholangitis Post\u2010Cholecystectomy Course"],"prefix":"10.1002","volume":"13","author":[{"given":"Faris Bandar","family":"Alrashdan","sequence":"first","affiliation":[{"name":"Head of Gastroenterology Department King Salman Specialist Hospital, Hail Health Cluster  Hail Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramy Mahmoud Fathy","family":"Elbarody","sequence":"additional","affiliation":[{"name":"Head of Gastroenterology Department King Salman Specialist Hospital, Hail Health Cluster  Hail Saudi 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Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6751-619X","authenticated-orcid":false,"given":"Bisher","family":"Sawaf","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Toledo Medical Center  Toledo Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nashaat Kamal Hamdy","family":"Elkalagi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine Arish University  Arish Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,24]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.4254\/wjh.v12.i6.312"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhepr.2020.100201"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750\u20101172\u20102\u201029"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.14309\/crj.0000000000000958"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43066\u2010023\u201000234\u20102"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radcr.2022.09.072"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinre.2024.102324"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jviscsurg.2019.02.006"}],"container-title":["Clinical Case 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