{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T09:11:20Z","timestamp":1790241080166,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T00:00:00Z","timestamp":1759708800000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Cardiac tuberculosis (TB) is a rare but important extrapulmonary form of TB that often presents diagnostic challenges due to nonspecific symptoms and its ability to mimic other cardiac conditions. We report the case of a 45\u2010year\u2010old woman with end\u2010stage renal disease secondary to granulomatosis with polyangiitis (GPA) who presented with fever and a seizure\u2010like episode. Initial investigations identified a cardiac mass located in the mitral\u2010aortic intervalvular fibrosa and a cavitary lung lesion. Although sputum PCR tests for\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Mycobacterium tuberculosis<\/jats:italic>\n                    <\/jats:styled-content>\n                    were negative, histopathological examination and PCR analysis of the surgically resected cardiac mass confirmed necrotizing granulomatous inflammation consistent with TB. This case highlights the difficulty of diagnosing cardiac TB, particularly in patients with overlapping conditions such as GPA, as the similar granulomatous histopathology can complicate differentiation. The initial false\u2010negative PCR results further emphasize limitations in current diagnostic tests, especially in immunocompromised hosts or atypical presentations. Given the complex interplay between cardiac TB and GPA, a multidisciplinary approach is essential for accurate diagnosis and management, with early recognition and tissue sampling critical to improving patient outcomes.\n                  <\/jats:p>","DOI":"10.1002\/ccr3.70949","type":"journal-article","created":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T05:02:36Z","timestamp":1759813356000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Navigating Diagnostic Dilemmas in Cardiology: A Rare Case Report of Tuberculosis Presenting as a Cardiac Abscess"],"prefix":"10.1002","volume":"13","author":[{"given":"Fariba","family":"Bayat","sequence":"first","affiliation":[{"name":"Shahid Beheshti University of Medical Sciences  Tehran, Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4900-5931","authenticated-orcid":false,"given":"Sepideh","family":"Jame Bozorgi","sequence":"additional","affiliation":[{"name":"Cardiology Shahid Beheshti University of Medical Sciences  Tehran, Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Khani","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Center Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4866-2623","authenticated-orcid":false,"given":"Mehrdad","family":"Jafari Fesharaki","sequence":"additional","affiliation":[{"name":"Department of Cardiology, School of Medicine Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdoulhamid","family":"Bagheri","sequence":"additional","affiliation":[{"name":"Shahid Beheshti University of Medical Sciences  Tehran, Tehran 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