{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T09:10:36Z","timestamp":1790241036173,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T00:00:00Z","timestamp":1760400000000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Lofgren syndrome is an acute and pathognomonic form of sarcoidosis characterized by fever, hilar lymphadenopathy, arthritis, and erythema nodosum (EN). We report a 35\u2010year\u2010old female patient from Ethiopia who presented with a 4\u2010day history of arthritis involving bilateral ankles, knees, and wrists associated with fever and skin lesions typical of EN. Chest imaging (X\u2010ray and computed tomography (CT) scan) revealed bilateral hilar and mediastinal lymphadenopathy as well as perilymphatic nodules in the mid and upper zones of both lungs. Workup for alternative diagnoses, including tuberculosis, was negative. After the diagnosis of Lofgren syndrome was made, she was started on a low dose of prednisolone, which resulted in a prompt and marked improvement in her symptoms.<\/jats:p>","DOI":"10.1002\/ccr3.71185","type":"journal-article","created":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T06:12:12Z","timestamp":1760508732000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Lofgren Syndrome in a 35\u2010Year\u2010Old Female: A Case Report"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-6923-1753","authenticated-orcid":false,"given":"Abel Tenaw","family":"Tasamma","sequence":"first","affiliation":[{"name":"School of Medicine College of Health Sciences, Addis Ababa University  Addis Ababa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-0064-7236","authenticated-orcid":false,"given":"Sebhatleab Teju","family":"Mulate","sequence":"additional","affiliation":[{"name":"School of Medicine College of Health Sciences, Addis Ababa University  Addis Ababa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etsegenet Yayut","family":"Munie","sequence":"additional","affiliation":[{"name":"School of Medicine College of Health Sciences, Addis Ababa University  Addis Ababa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kasim Arga","family":"Berkaga","sequence":"additional","affiliation":[{"name":"School of Medicine College of Health Sciences, Addis Ababa University  Addis Ababa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulrahim","family":"Mehadi","sequence":"additional","affiliation":[{"name":"John H. Stroger Jr. Hospital of Cook County  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nebiyu Getachew","family":"Mekonnen","sequence":"additional","affiliation":[{"name":"School of Medicine College of Health Sciences, Addis Ababa University  Addis Ababa Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,14]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-014-8450-y"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(99)00223-5"},{"key":"e_1_2_12_4_1","first-page":"67","article-title":"Manifestations of Sarcoidosis. 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American Thoracic Society\/European Respiratory Society\/World Association of Sarcoidosis and Other Granulomatous Disorders","volume":"16","author":"Hunninghake G. W.","year":"1999","journal-title":"Sarcoidosis, Vasculitis, and Diffuse Lung Diseases"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.160.2.ats4-99"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.61.6.499"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.5114\/reum.2017.71644"},{"issue":"2","key":"e_1_2_12_18_1","first-page":"1","article-title":"A Sporadic Case of Lofgren Syndrome in a 32 Year Old Nigerian Man. A Rare Finding in Sub\u2010Saharan Africa: A Case Report","volume":"6","author":"Ogunkoya J. O.","year":"2022","journal-title":"International Journal of Medical Reviews and Case Reports"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.71185","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.71185","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.71185","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T08:52:12Z","timestamp":1790239932000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.71185"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":17,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1002\/ccr3.71185"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.71185","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"2025-01-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71185"}}