{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T09:11:01Z","timestamp":1790241061166,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:00:00Z","timestamp":1761004800000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Refractory hypothyroidism is not uncommon in patients treated with oral levothyroxine, and it represents a challenge for clinicians as regards a physiopathological diagnosis and the most appropriate long\u2010term therapeutic management in order to restore normal TSH concentrations.<\/jats:p>","DOI":"10.1002\/ccr3.71289","type":"journal-article","created":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T04:54:49Z","timestamp":1761108889000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Refractory Hypothyroidism: Unexpected Outcome During Treatment of Giant Cell Arteritis"],"prefix":"10.1002","volume":"13","author":[{"given":"Elise","family":"Deprince","sequence":"first","affiliation":[{"name":"Department of Endocrinology, Metabolic Diseases and Nutrition, Cardiovascular and Metabolic Unit Larrey University Hospital  Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Solange","family":"Grunenwald","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Metabolic Diseases and Nutrition, Cardiovascular and Metabolic Unit Larrey University Hospital  Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celine","family":"Mouly","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Metabolic Diseases and Nutrition, Cardiovascular and Metabolic Unit Larrey University Hospital  Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Benoit","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Metabolic Diseases and Nutrition, Cardiovascular and Metabolic Unit Larrey University Hospital  Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5391-7582","authenticated-orcid":false,"given":"Philippe J.","family":"Caron","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Metabolic Diseases and Nutrition, Cardiovascular and Metabolic Unit Larrey University Hospital  Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,21]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40618\u2010017\u20100706\u2010y"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eprac.2023.09.003"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/MED.0000000000000003"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000504218"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgad132"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1210\/jendso\/bvaf017"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.2018\u201000168"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa043903"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2019.0256"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijem.ijem_188_21"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.2018\u201000119"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ansa.202200067"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2021.664839"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2020.00495"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0b013e3181646118"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.090152"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijpm.ijpm_124_22"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.71289","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.71289","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.71289","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T08:49:10Z","timestamp":1790239750000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.71289"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":17,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1002\/ccr3.71289"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.71289","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"2025-03-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71289"}}