{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:12:38Z","timestamp":1777587158122,"version":"3.51.4"},"reference-count":34,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T00:00:00Z","timestamp":1761782400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Acquired methemoglobinemia can rarely be caused by acute nitrobenzene poisoning, presenting as oxygen\u2010unresponsive, life\u2010threatening hypoxia. We discuss a case of a 19\u2010year\u2010old female who attempted suicide through intentional nitrobenzene poisoning. She presented to the emergency department with progressive cyanosis, severe abdominal pain, and dyspnea. Her symptoms were suggestive of methemoglobinemia, which was confirmed through arterial blood gas (ABG) analysis, revealing a methemoglobin level of 37.5%. Treatment included intravenous methylene blue, vitamin C, and supportive care, leading to clinical improvement. This case highlights the critical need for early recognition and timely administration of methylene blue, particularly in resource\u2010limited settings where delayed diagnosis can increase morbidity. It also signifies the importance of integrating psychiatric evaluation and mental health support in cases of intentional poisoning to prevent recurrence.<\/jats:p>","DOI":"10.1002\/ccr3.71329","type":"journal-article","created":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:04:55Z","timestamp":1761894295000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A Cyanotic Dilemma: Nitrobenzene Poisoning\u2014A Case Report"],"prefix":"10.1002","volume":"13","author":[{"given":"Janmejay Kumar","family":"Singh","sequence":"first","affiliation":[{"name":"Teerthanker Mahaveer University Medical College and Research Centre  Moradabad Uttar Pradesh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian","family":"Villaroman","sequence":"additional","affiliation":[{"name":"University of the East Ramon Magsaysay Memorial Medical Center  Quezon City Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaehoon","family":"Kim","sequence":"additional","affiliation":[{"name":"Catholic University of Daegu School of Medicine  Daegu South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3717-2781","authenticated-orcid":false,"given":"Ghazal","family":"Majidi","sequence":"additional","affiliation":[{"name":"Tabriz University of Medical Sciences Faculty of Medicine  Tabriz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana Stefanie Rojas","family":"Torres","sequence":"additional","affiliation":[{"name":"The Lundquist Institute for Biomedical Innovation, Torrance  Torrance California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mrinal","family":"Bhandari","sequence":"additional","affiliation":[{"name":"The Lundquist Institute for Biomedical Innovation  Torrance California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fazeela","family":"Bibi","sequence":"additional","affiliation":[{"name":"Jinnah Sindh Medical University  Karachi Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6138-6684","authenticated-orcid":false,"given":"Khalil E. L.","family":"Abdi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Pharmacy of Rabat Mohammed V University  Rabat Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ujjwal","family":"Dutta","sequence":"additional","affiliation":[{"name":"GMERS Medical College Gotri  Vadodara India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sojitra","family":"Vani","sequence":"additional","affiliation":[{"name":"Bavadia Hospital  Una India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,30]]},"reference":[{"key":"e_1_2_14_2_1","unstructured":"Agency for Toxic Substances and Disease Registry (ATSDR) \u201cToxicological Profile for Nitrobenzene \u201dU.S. Department of Health and Human Services Public Health Service."},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2022.104553"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/0972\u20105229.126089"},{"issue":"10","key":"e_1_2_14_5_1","article-title":"High\u2010Dose Vitamin C as an Alternative Therapy in Methemoglobinemia","volume":"9","author":"Mohammed A.","year":"2018","journal-title":"International Journal of Case Reports and Images"},{"issue":"5","key":"e_1_2_14_6_1","first-page":"749","article-title":"Methemoglobinemia Unmasked: A Deep Dive Into Poisoning Cases and Treatment Strategies","volume":"14","author":"Chandrawanshi D. 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