{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:36:09Z","timestamp":1786977369362,"version":"build-2736575974"},"reference-count":9,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T00:00:00Z","timestamp":1761523200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Acute hepatic failure is a rare but critical complication of Crimean\u2010Congo hemorrhagic fever (CCHF). This case presents acute hepatic failure with liver enzyme elevation and thrombocytopenia. The patient responded well to treatment that included ribavirin, lactulose, rifaximin, and supportive therapies. This case highlights the importance of early management in CCHF cases, and recovery even in dire clinical scenarios.<\/jats:p>","DOI":"10.1002\/ccr3.71358","type":"journal-article","created":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T07:06:57Z","timestamp":1761548817000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Acute Hepatic Failure in Crimean\u2010Congo Hemorrhagic Fever: A Case Report"],"prefix":"10.1002","volume":"13","author":[{"given":"Ahmed Abdulhussain","family":"Shahatta","sequence":"first","affiliation":[{"name":"College of Medicine Thi\u2010Qar University  Thi\u2010Qar Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6259-1045","authenticated-orcid":false,"given":"Sajjad Ghanim","family":"Al\u2010Badri","sequence":"additional","affiliation":[{"name":"College of Medicine University of Baghdad  Baghdad Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khadija","family":"Naeem","sequence":"additional","affiliation":[{"name":"Department of Medicine Nishtar Hospital  Multan Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulrahman Khaldoon","family":"Hamid","sequence":"additional","affiliation":[{"name":"College of Medicine Alexandria University  Alexandria Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3048-0984","authenticated-orcid":false,"given":"Nabeel","family":"Al\u2010Fatlawi","sequence":"additional","affiliation":[{"name":"College of Medicine University of Baghdad  Baghdad Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali Saad","family":"Al\u2010Shammari","sequence":"additional","affiliation":[{"name":"College of Medicine University of Baghdad  Baghdad Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3496-5158","authenticated-orcid":false,"given":"Sabry Babiker H.","family":"Sayed","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health Sciences International University of Africa  Khartoum Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbas Hamza","family":"Abbas","sequence":"additional","affiliation":[{"name":"College of Medicine University of Basra  Basra Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali Azeez","family":"Shlaka","sequence":"additional","affiliation":[{"name":"Al\u2010Hussain Teaching Hospital  Thi\u2010Qar Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,27]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.17842"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2010.10.005"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473\u20103099(06)70435\u20102"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.26719\/2024.30.8.570"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjgh\u20102018\u2010001114"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medmal.2019.09.005"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2409.171709"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.14744\/nci.2023.09815"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2304722120"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.71358","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T05:52:56Z","timestamp":1765259576000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.71358"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,27]]},"references-count":9,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1002\/ccr3.71358"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.71358","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,27]]},"assertion":[{"value":"2024-11-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71358"}}