{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T14:32:45Z","timestamp":1790260365832,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T00:00:00Z","timestamp":1762905600000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>An eight\u2010year\u2010old girl presented with a first episode of focal seizure and transient loss of consciousness. Brain MRI revealed a large subacute infarct in the left fronto\u2010parieto\u2010temporal region, and MR angiography showed bilateral supraclinoid internal carotid and proximal posterior cerebral artery narrowing with extensive basal collateral formation, consistent with Moyamoya disease. The absence of aneurysm or arteriovenous malformation excluded other vascular anomalies. She was managed with hypertonic saline, intravenous antibiotics, and antiplatelet therapy, followed by stabilization and referral for surgical revascularization. This case underscores the importance of maintaining a high index of suspicion for Moyamoya disease in children presenting with new\u2010onset seizures or stroke\u2010like episodes. Early neuroimaging and multidisciplinary management are essential to prevent further ischemic injury and optimize neurological outcomes.<\/jats:p>","DOI":"10.1002\/ccr3.71384","type":"journal-article","created":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T04:19:33Z","timestamp":1763007573000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Moyamoya Disease in an Eight\u2010Year\u2010Old Female Child\u2014A Case Report"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-1349-1842","authenticated-orcid":false,"given":"Disha","family":"Thapa","sequence":"first","affiliation":[{"name":"Gujarat Medical Education and Research Society  Vadnagar Gujarat India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2551-4983","authenticated-orcid":false,"given":"Sai Priya","family":"Nimmagadda","sequence":"additional","affiliation":[{"name":"Gandhi Medical College  Hyderabad Telangana India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-9930-0147","authenticated-orcid":false,"given":"Betsy Annie","family":"Philip","sequence":"additional","affiliation":[{"name":"Kerala State Medical Council  Trivandrum India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-0685-8783","authenticated-orcid":false,"given":"Shreya Milind","family":"Kawade","sequence":"additional","affiliation":[{"name":"Government Medical College Nagpur  Nagpur India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-6616-2405","authenticated-orcid":false,"given":"Abhisar","family":"Rohila","sequence":"additional","affiliation":[{"name":"Gujarat Medical Education and Research Society  Vadnagar Gujarat India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5110-1544","authenticated-orcid":false,"given":"Mihirkumar P.","family":"Parmar","sequence":"additional","affiliation":[{"name":"Gujarat Medical Education and Research Society  Vadnagar Gujarat India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1042-5390","authenticated-orcid":false,"given":"Saleh","family":"Mohammed","sequence":"additional","affiliation":[{"name":"Faridpur Medical College Hospital  Faridpur Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,12]]},"reference":[{"key":"e_1_2_20_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000448314"},{"key":"e_1_2_20_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0804622"},{"key":"e_1_2_20_4_1","doi-asserted-by":"publisher","DOI":"10.2176\/jns\u2010nmc.2022\u20100072"},{"key":"e_1_2_20_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000093238"},{"key":"e_1_2_20_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474\u20104422(22)00165\u2010X"},{"key":"e_1_2_20_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/jhg.2010.103"},{"key":"e_1_2_20_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10143\u2010018\u20100994\u20105"},{"key":"e_1_2_20_9_1","doi-asserted-by":"crossref","DOI":"10.1093\/med\/9780195394023.001.0001","volume-title":"The Practice of Emergency and Critical Care Neurology","author":"Wijdicks E. 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Complication H\u00e9morragique D'une Forme S\u00e9v\u00e8re de Maladie de Moyamoya [Hemorrhagic Moyamoya Disease]","volume":"75","author":"Angelozzi V.","year":"2020","journal-title":"Revue M\u00e9dicale De Li\u00e8ge"},{"key":"e_1_2_20_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/09084282.2012.721147"},{"key":"e_1_2_20_21_1","doi-asserted-by":"publisher","DOI":"10.3171\/2000.01.FOCUS08306"},{"key":"e_1_2_20_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2021.11.026"},{"key":"e_1_2_20_23_1","doi-asserted-by":"publisher","DOI":"10.3390\/neurolint16040065"},{"key":"e_1_2_20_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12975\u2010021\u201000940\u20102"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.71384","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T05:51:36Z","timestamp":1765259496000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.71384"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":23,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1002\/ccr3.71384"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.71384","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"2025-06-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71384"}}