{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T06:26:52Z","timestamp":1765261612041,"version":"3.46.0"},"reference-count":41,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T00:00:00Z","timestamp":1762905600000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>This case report aimed to present an accurate and minimally invasive approach to retrieve a separated instrument beyond the apical foramen, using a 3\u2010dimensional (3D) printing guide and trephine bur. A 31\u2010year\u2010old female patient was referred for treatment of the left maxillary central incisor, complaining that a fractured file had been pushed out of the root canal by her previous dentist approximately 2\u2009weeks prior. On clinical examination, tooth #9 was temporarily sealed and slightly tender on percussion. Periodontal probing was within normal limits. Radiographic and cone\u2010beam computed tomographic imaging revealed a periapical radiolucent lesion at tooth #9, with a separated instrument approximately 3\u2009mm long extruded approximately 2\u2009mm beyond the apical foramen and 4\u2009mm deep in the bone. The tooth was diagnosed with symptomatic apical periodontitis. After root canal treatment, endodontic surgery was performed to retrieve the extraradicular separated instrument with the aid of a 3D printing guide and trephine bur. The root end was ultrasonically prepared and retrograde filled. The patient was asymptomatic when recalled 3\u2009months and 2\u2009years after the surgery, and the follow\u2010up periapical radiograph showed successful healing of the periapical lesion. This method enables a single\u2010step operation, completing the removal of the extraradicular separated instrument while performing osteotomy.<\/jats:p>","DOI":"10.1002\/ccr3.71444","type":"journal-article","created":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T04:16:41Z","timestamp":1763007401000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Removal of Extraradicular Separated Instrument by Targeted Endodontic Microsurgery Using the\n                    <scp>3D<\/scp>\n                    \u2010Printed Guide and Trephine: A Case Report"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3844-7679","authenticated-orcid":false,"given":"Lin","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Endodontics Stomatological Hospital of Chongqing Medical University  Chongqing China"},{"name":"Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences Stomatological Hospital of Chongqing Medical University  Chongqing China"},{"name":"Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education  Chongqing China"},{"name":"Chongqing Municipal Health Commission Key Laboratory of Oral Biomedical Engineering  Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Endodontics Stomatological Hospital of Chongqing Medical University  Chongqing China"},{"name":"Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences Stomatological Hospital of Chongqing Medical University  Chongqing China"},{"name":"Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education  Chongqing China"},{"name":"Chongqing Municipal Health Commission Key Laboratory of Oral Biomedical Engineering  Chongqing 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