{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T22:12:36Z","timestamp":1766268756655,"version":"3.46.0"},"reference-count":16,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,11,16]],"date-time":"2025-11-16T00:00:00Z","timestamp":1763251200000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Toxic Epidermal Necrolysis (TEN) is an acute, uncommon, extensive, and life\u2010threatening dermatological condition, which is caused by a delayed adverse response of the skin to a particular type of drug. Herein, we report a 41\u2010year\u2010old female known case of IgA nephropathy admitted for having TEN after a recent intake of Deflazacort, developed systemic candidiasis during admission, and was successfully treated with oral fluconazole. Early detection of diffuse pustular and hemorrhagic crusted lesions with immediate antifungal treatment in TEN is crucial to prevent systemic complications and enhance patient outcomes.<\/jats:p>","DOI":"10.1002\/ccr3.71451","type":"journal-article","created":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T04:30:03Z","timestamp":1763353803000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Recognition of Diffuse Pustules and Hemorrhagic Crusts as Early Warning Signs of Invasive Candidiasis in a Patient With Toxic Epidermal Necrolysis"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-7324-0347","authenticated-orcid":false,"given":"Saman","family":"Al\u2010Zahawi","sequence":"first","affiliation":[{"name":"Department of Dermatology Razi Hospital, Tehran University of Medical Sciences (TUMS)  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatemeh","family":"Saberi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Razi Hospital, Tehran University of Medical Sciences (TUMS)  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tahereh","family":"Soori","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Razi Hospital, Tehran University of Medical Sciences (TUMS)  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elham","family":"Yousefi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Razi Hospital, Tehran University of Medical Sciences (TUMS)  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamran","family":"Balighi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Razi Hospital, Tehran University of Medical Sciences (TUMS)  Tehran Iran"},{"name":"Autoimmune Bullous Diseases Research Center Razi Hospital, Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,16]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-017-8654-z"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.krcp.2014.08.002"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.3889\/oamjms.2018.148"},{"volume-title":"Dermatology e\u2010Book","year":"2012","author":"Bolognia J. 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M.LabibandC.Milroy \u201cToxic Epidermal Necrolysis \u201d (2021)."},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjd\/ljae252"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/1757-1626-2-9071"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(86)80148-2"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000024392"},{"issue":"13","key":"e_1_2_11_11_1","first-page":"1233","article-title":"Losartan\u2010Induced Stevens\u2010Johnson Syndrome in a Geriatric Patient","volume":"169","author":"Bonnici H.","year":"2007","journal-title":"Ugeskrift for Laeger"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.750173"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/03000605231223059"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2019-230144"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/14740338.2022.2045945"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0163-4453(93)92761-K"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0305-4179(95)00140-9"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.71451","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T05:54:08Z","timestamp":1765259648000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.71451"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":16,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1002\/ccr3.71451"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.71451","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"2025-07-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71451"}}