{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T06:26:39Z","timestamp":1765261599806,"version":"3.46.0"},"reference-count":38,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,11,16]],"date-time":"2025-11-16T00:00:00Z","timestamp":1763251200000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Amyotrophic lateral sclerosis (ALS) is a chronic, progressive neurodegenerative disease for which there is a lack of effective treatment. This case report describes a 49\u2010year\u2010old male with ALS who presented with dysphagia, dysarthria, dyskinesia, sleep disorders, anxiety, and depression. Following 45\u2009days of early multidisciplinary rehabilitation, the patient demonstrated significant improvement in swallowing and speech function, alleviation of non\u2010motor symptoms, and maintenance of motor function. Notably, he retained the ability to consume soft foods at a two\u2010year follow\u2010up. This case highlights the vital role of early multidisciplinary rehabilitation in the comprehensive management of ALS.<\/jats:p>","DOI":"10.1002\/ccr3.71486","type":"journal-article","created":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T04:11:57Z","timestamp":1763352717000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Early Multidisciplinary Rehabilitation Improves Swallowing and Speech Function in a Patient With Amyotrophic Lateral Sclerosis"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5988-9199","authenticated-orcid":false,"given":"Yue","family":"Hu","sequence":"first","affiliation":[{"name":"Department of Neurology and Neurological Rehabilitation Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurological Rehabilitation Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danmei","family":"Lan","sequence":"additional","affiliation":[{"name":"Department of Neurology and Neurological Rehabilitation Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), School of Medicine, Tongji University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,16]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(17)31287\u20104"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(10)61156\u20107"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2018.04.007"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181bc01a4"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmr.2008.04.004"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2024.1389146"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1044\/2022_jslhr\u201021\u201000567"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9072314"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.74.9.1258"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000180717.29273.12"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0022\u2010510x(99)00210\u20105"},{"issue":"2","key":"e_1_2_12_13_1","first-page":"S7","article-title":"Measuring Balance in the Elderly: Validation of an Instrument","volume":"83","author":"Berg K. O.","year":"1992","journal-title":"Canadian Journal of Public Health"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0895\u20104356(89)90065\u20106"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.3109\/13682828009112541"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.3109\/21678421.2013.805784"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2044\u20108341.1959.tb00467.x"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.23.1.56"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1989.00520460115022"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/nur.4770130405"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00034805"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.6576"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165\u20101781(89)90047\u20104"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(22)01272\u20107"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.5935\/1808\u20108694.20130061"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1080\/17482960701262376"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00455\u2010002\u20100074\u20103"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1177\/0884533613476554"},{"issue":"1","key":"e_1_2_12_29_1","first-page":"35","article-title":"Augmentative and Alternative Communication Improves Quality of Life in the Early Stages of Amyotrophic Lateral Sclerosis","volume":"34","author":"Maresca G.","year":"2019","journal-title":"Functional Neurology"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnrt.2024.100138"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.26599\/JNR.2020.9040003"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.24202"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0022\u2010510x(01)00610\u20104"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.10597"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2009.11.051"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.24990"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.4103\/0028\u20103886.232327"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415\u2010019\u201009615\u20103"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2020.01.028"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.71486","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T05:52:32Z","timestamp":1765259552000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.71486"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":38,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1002\/ccr3.71486"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.71486","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"2025-06-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71486"}}