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The patient, with a history of ischemic heart disease and severe left ventricular dysfunction (ejection fraction 25%), required primary prevention of sudden cardiac death. Due to anatomical challenges with transvenous ICD placement and no need for pacing or resynchronization, an S\u2010ICD was selected. Pre\u2010procedural screening was modified by reversing electrode positions to accommodate the right\u2010sided heart, ensuring eligibility across all sensing vectors. The S\u2010ICD was implanted using a two\u2010incision technique, positioning the generator in the right midaxillary line and the electrode along the left parasternal area. Defibrillation threshold testing confirmed effective termination of induced ventricular fibrillation with a 60\u2009J shock. No complications occurred, and 1\u2010month follow\u2010up verified normal device function. This case demonstrates the adaptability and safety of S\u2010ICD implantation in dextrocardia, emphasizing tailored screening and procedural adjustments. A review of existing literature shows consistent success with S\u2010ICDs in similar patients, though device placement varies. This report adds to the evidence supporting S\u2010ICD use in complex congenital anatomies, providing valuable guidance for clinicians.<\/jats:p>","DOI":"10.1002\/ccr3.71509","type":"journal-article","created":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T06:02:31Z","timestamp":1763704951000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Successful Right Sided Subcutaneous Implantable Cardioverter\u2010Defibrillator Implantation in Situs Inversus Dextrocardia: A Case Report and Literature Review"],"prefix":"10.1002","volume":"13","author":[{"given":"Bahareh","family":"Karimian","sequence":"first","affiliation":[{"name":"Cardiac Electrophysiology Research Center Rajaie Cardiovascular Institute  Tehran Iran"},{"name":"Department of Electrophysiology Rajaie Cardiovascular Institute  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Majid","family":"Haghjoo","sequence":"additional","affiliation":[{"name":"Cardiac Electrophysiology Research Center Rajaie Cardiovascular Institute  Tehran Iran"},{"name":"Department of Electrophysiology Rajaie Cardiovascular Institute  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1535-0025","authenticated-orcid":false,"given":"Akam","family":"Ramezani","sequence":"additional","affiliation":[{"name":"Cardiac Electrophysiology Research Center Rajaie Cardiovascular Institute  Tehran Iran"},{"name":"Department of Electrophysiology Rajaie Cardiovascular Institute  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehrdad","family":"Khajehei","sequence":"additional","affiliation":[{"name":"Cardiac Electrophysiology Research Center Rajaie Cardiovascular Institute  Tehran Iran"},{"name":"Department of Electrophysiology Rajaie Cardiovascular Institute  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,20]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2007.02.095"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.7812\/TPP\/18.244"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJGM.S295444"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2013.255109"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2024.12.003"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.02.047"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu112"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.01.018"},{"issue":"11","key":"e_1_2_11_10_1","first-page":"1562","article-title":"Cardiac Resynchronization Therapy Upgrade in a Patient With Dextrocardia and Situs Inversus","volume":"11","author":"Scott P. 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