{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T10:34:22Z","timestamp":1766399662427,"version":"3.48.0"},"reference-count":11,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T00:00:00Z","timestamp":1764288000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Mpox, primarily known for cutaneous and mucosal manifestations, can present atypically. This case reports a rare digestive form with peritonitis in a 16\u2010year\u2010old girl. A febrile adolescent presented with acute abdominal pain, peritonitis, systemic inflammation, anemia, and ionic disturbances. Imaging revealed intra\u2010abdominal effusion, and polymerase chain reaction (PCR) confirmed Mpox virus infection in surgical specimens. The diagnosis was confirmed by PCR performed on intraoperative pus, targeting the F3L gene of the\n                    <jats:italic>Orthopoxvirus<\/jats:italic>\n                    genus. The test was processed at the National Institute for Biomedical Research (INRB, Goma). The result was positive, with a cycle threshold (Ct) value of 24. Peritonitis was attributed to Mpox. Laparotomy showed fatty nodules and a retrouterine purulent collection. Management included surgery, antibiotic (erythromycin) therapy, ionic correction, and intensive care, leading to recovery by Day 30. This case highlights a severe, atypical Mpox presentation, emphasizing its inclusion in the differential diagnoses of acute surgical abdomen during outbreaks. Early diagnosis and multidisciplinary care are crucial, warranting further study on Mpox's digestive tropism.\n                  <\/jats:p>","DOI":"10.1002\/ccr3.71547","type":"journal-article","created":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T05:29:33Z","timestamp":1764394173000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Mpox With Digestive Manifestations in a 16\u2010Year\u2010Old Adolescent Girl: A Case Report"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6088-2629","authenticated-orcid":false,"given":"Criss Koba","family":"Mjumbe","sequence":"first","affiliation":[{"name":"Faculty of Medicine University of Lubumbashi  Lubumbashi DR Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James Mushamalirwa","family":"Bafurume","sequence":"additional","affiliation":[{"name":"Faculty of Public Health Simon Kimbagu University of Bukavu (USK)  Bukavu DR Congo"},{"name":"Panzi General Reference Hospital, HGR Panzi  Bukavu DR Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edouard Mbaya","family":"Munianji","sequence":"additional","affiliation":[{"name":"Kananga School of Public Health University of Kananga  Kananga DR Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-8547-3153","authenticated-orcid":false,"given":"Christian","family":"Tague","sequence":"additional","affiliation":[{"name":"Department of Research Medical Research Circle (MedReC)  Goma DR Congo"},{"name":"International Veterinary Vaccinology Network The Roslin Institute University of Edinburgh  Edinburgh UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9393-1215","authenticated-orcid":false,"given":"Aymar","family":"Akilimali","sequence":"additional","affiliation":[{"name":"Department of Research Medical Research Circle (MedReC)  Goma DR Congo"},{"name":"International Veterinary Vaccinology Network The Roslin Institute University of Edinburgh  Edinburgh UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,28]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2022.103975"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2022.05.058"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2019.03.001"},{"key":"e_1_2_9_5_1","first-page":"83","article-title":"When Monkey Pox Manages to Escape From Africa","volume":"8","author":"Chastel C.","year":"2004","journal-title":"Virology"},{"key":"e_1_2_9_6_1","first-page":"12","article-title":"Monkeypox, A Paradigm of Emerging and Then Re\u2010Emerging Disease","volume":"34","author":"Georges A. 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WHO Advisory Committee on Variolosis Virus Research","volume":"99","author":"WHO","year":"2024","journal-title":"REH"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/v17060753"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473\u20103099(22)00228\u20106"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2207323"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.137363.2"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmmb.2024.100704"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.71547","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T10:30:33Z","timestamp":1766399433000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.71547"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,28]]},"references-count":11,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1002\/ccr3.71547"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.71547","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2025,11,28]]},"assertion":[{"value":"2025-08-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71547"}}