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This case discusses AOSD complicated by HLH in a 29\u2010year\u2010old female, emphasizing prompt recognition and management.<\/jats:p>","DOI":"10.1002\/ccr3.71650","type":"journal-article","created":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T05:37:16Z","timestamp":1765777036000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Adult\u2010Onset Still's Disease Complicated by Secondary Hemophagocytic Lymphohistiocytosis: A Case Report"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6561-321X","authenticated-orcid":false,"given":"Vasileios","family":"Patriarcheas","sequence":"first","affiliation":[{"name":"First Propaedeutic Department of Internal Medicine Aristotle University of Thessaloniki, AHEPA University Hospital  Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasiliki","family":"Gougoula","sequence":"additional","affiliation":[{"name":"First Propaedeutic Department of Internal Medicine Aristotle University of Thessaloniki, AHEPA University Hospital  Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michail","family":"Makris","sequence":"additional","affiliation":[{"name":"First Propaedeutic Department of Internal Medicine Aristotle University of Thessaloniki, AHEPA University Hospital  Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Athanasios","family":"Penopoulos","sequence":"additional","affiliation":[{"name":"First Propaedeutic Department of Internal Medicine Aristotle University of Thessaloniki, AHEPA University Hospital  Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleftheria","family":"Ztriva","sequence":"additional","affiliation":[{"name":"First Propaedeutic Department of Internal Medicine Aristotle University of Thessaloniki, AHEPA University Hospital  Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stavroula","family":"Bountola","sequence":"additional","affiliation":[{"name":"First Propaedeutic Department of Internal Medicine Aristotle University of Thessaloniki, AHEPA University Hospital  Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theodoros","family":"Dimitroulas","sequence":"additional","affiliation":[{"name":"4th Department of Internal Medicine Aristotle University of Thessaloniki, Hippokration General Hospital  Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christos","family":"Savopoulos","sequence":"additional","affiliation":[{"name":"First Propaedeutic Department of Internal Medicine Aristotle University of Thessaloniki, AHEPA University Hospital  Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgia","family":"Kaiafa","sequence":"additional","affiliation":[{"name":"First Propaedeutic Department of Internal Medicine Aristotle University of Thessaloniki, AHEPA University Hospital  Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,14]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10040733"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2018.07.018"},{"issue":"3","key":"e_1_2_13_4_1","first-page":"424","article-title":"Preliminary Criteria for Classification of Adult Still's Disease","volume":"19","author":"Yamaguchi M.","year":"1992","journal-title":"Journal of Rheumatology"},{"volume-title":"Adult\u2010Onset Still's Disease: Clinical Manifestations and Diagnosis","year":"2025","author":"Mandl L. 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