{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T00:13:33Z","timestamp":1769127213188,"version":"3.49.0"},"reference-count":8,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T00:00:00Z","timestamp":1767657600000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>DYNC2I2<\/jats:italic>\n                    \u2010related Short\u2010Rib Thoracic Dysplasia 11 can present prenatally with prominent limb shortening and polydactyly as the primary ultrasound findings, while classic thoracic abnormalities may be subtle. This case highlights the condition's clinical heterogeneity and underscores the importance of genetic testing for accurate diagnosis and counseling.\n                  <\/jats:p>","DOI":"10.1002\/ccr3.71708","type":"journal-article","created":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T15:31:52Z","timestamp":1767713512000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Rare Case of Prenatal Short\u2010Rib Thoracic Dysplasia 11 Subtype With Compound Heterozygous Variants in the\n                    <scp>\n                      <i>DYNC2I2<\/i>\n                    <\/scp>\n                    Gene: Presenting Polydactyly and Shortened Limbs"],"prefix":"10.1002","volume":"14","author":[{"given":"Zhihui","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics Wenzhou Central Hospital  Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heqin","family":"Guan","sequence":"additional","affiliation":[{"name":"Department of Reproductive Medicine Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University  Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ximei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics Wenzhou Central Hospital  Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jielan","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Radiology Wenzhou Central Hospital  Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Pan","sequence":"additional","affiliation":[{"name":"Department of Central Laboratory Wenzhou Central Hospital  Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xueqin","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Wenzhou Central Hospital  Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9971-8332","authenticated-orcid":false,"given":"Xutao","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Central Laboratory Wenzhou Central Hospital  Zhejiang China"},{"name":"Yikon Genomics co., Ltd  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,6]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.63132"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2023.1125473"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2023.1075187"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2023.2205985"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2013.10.003"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.17816\/PTORS91116"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2013.10.007"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/gim.2015.30"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.71708","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.71708","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.71708","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T07:17:30Z","timestamp":1769066250000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.71708"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1002\/ccr3.71708"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.71708","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-04-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71708"}}