{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T23:51:06Z","timestamp":1769125866822,"version":"3.49.0"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,11]],"date-time":"2026-01-11T00:00:00Z","timestamp":1768089600000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Leprosy and tuberculosis (TB) are both chronic granulomatous infections caused by bacilli of the genus\n                    <jats:italic>Mycobacterium<\/jats:italic>\n                    . The simultaneous occurrence of cutaneous tuberculosis and leprosy is rare. We report a 56\u2010year\u2010old male presenting with painful erythematous nodules and plaques over the face and extremities for 1\u2009week, along with asymptomatic right axillary lesions for 1\u2009year. Examination revealed tender nodules and plaques with ulceration on the face and extremities, and firm, matted subcutaneous nodules with sinus tracts in the axilla. Sensory loss in a glove\u2010and\u2010stocking distribution and peripheral nerve enlargement were also noted. Slit\u2010skin smear demonstrated a Bacteriological Index of 6+, while histopathology of the axillary lesion showed caseous necrosis with epithelioid granulomas. The patient was diagnosed with lepromatous leprosy in type 2 lepra reaction with scrofuloderma and treated with modified multibacillary multidrug therapy, anti\u2010tubercular therapy, and corticosteroids, achieving a favorable clinical response. This case report aims to describe a rare co\u2010occurrence of leprosy and tuberculosis, highlighting the immunological interplay between the two conditions and the importance of comprehensive diagnostic evaluation and individualized management in endemic settings.\n                  <\/jats:p>","DOI":"10.1002\/ccr3.71842","type":"journal-article","created":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T03:35:31Z","timestamp":1768188931000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Coexistence of Scrofuloderma and Lepromatous Leprosy in Reaction: A Case Report"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7115-9137","authenticated-orcid":false,"given":"Anupa","family":"Khadka","sequence":"first","affiliation":[{"name":"Patan Academy of Health Sciences  Lalitpur Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-4699-9873","authenticated-orcid":false,"given":"Punam","family":"Mishra","sequence":"additional","affiliation":[{"name":"Pokhara Academy of Health Sciences  Kaski Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-8582-7109","authenticated-orcid":false,"given":"Akanshya","family":"Shrestha","sequence":"additional","affiliation":[{"name":"Nepal Armed Police Force Hospital  Kathmandu Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunawati","family":"Chaulagain","sequence":"additional","affiliation":[{"name":"Maharajgunj Medical Campus Institute of Medicine  Kathmandu Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,11]]},"reference":[{"key":"e_1_2_12_2_1","unstructured":"N.Parajuli A.Karki andA.Dhungana \u201cView of Cutaneous Tuberculosis Among Patients Presenting to Dermatology Outpatient Department of a Tertiary Care Centre: A Descriptive Cross\u2010Sectional Study \u201dhttps:\/\/www.jnma.com.np\/jnma\/index.php\/jnma\/article\/view\/7930\/4461."},{"key":"e_1_2_12_3_1","unstructured":"World Health Organization \u201cLeprosy Fact Sheet \u201d(2024) https:\/\/www.who.int\/news\u2010room\/fact\u2010sheets\/detail\/leprosy."},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.3855\/jidc.14308"},{"key":"e_1_2_12_5_1","article-title":"Co\u2010Infection With M. tuberculosis and M. leprae Case Report and Systematic Review","volume":"2","author":"Rajagopalan S.","year":"2012","journal-title":"International Journal of Mycobacteriology"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijmy.ijmy_83_23"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.136995"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.87.12.1923"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.47276\/lr.87.1.109"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trstmh.2008.04.015"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijd.IJD_715_16"},{"key":"e_1_2_12_12_1","first-page":"111","article-title":"A Lupus vulgaris and Borderline Tuberculoid Leprosy: An Interesting Co\u2010Occurrence","volume":"71","author":"Rao G. R.","year":"2025","journal-title":"Indian Journal of Dermatology, Venereology and Leprology"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2012.12-0433"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0011334"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.47276\/lr.74.4.319"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.71842","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.71842","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.71842","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T07:16:19Z","timestamp":1769066179000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.71842"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1002\/ccr3.71842"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.71842","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-11-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71842"}}