{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T00:03:06Z","timestamp":1769126586481,"version":"3.49.0"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T00:00:00Z","timestamp":1768694400000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>This case report describes the successful use of an augmented reality (AR) guidance system (XR90, MediView XR Inc., Cleveland Ohio) to assist in the percutaneous biopsy of a splenic mass performed in a minor procedure room. Traditional two\u2010dimensional (2D) imaging modalities such as ultrasound and computed tomography (CT) present limitations in depth perception, spatial orientation, and procedural ergonomics, particularly in anatomically complex and mobile regions like the spleen. The AR system integrates real\u2010time ultrasound, electromagnetic (EM) tracking, and pre\u2010procedural CT data to generate a 3D holographic overlay within a heads\u2010up display (HUD), enhancing operator spatial awareness and needle control. A 69\u2010year\u2010old male with a 6\u2009cm splenic mass underwent biopsy using the AR platform alongside ultrasound. The system enabled accurate needle placement, reduced cognitive load, and provided continuous visual confirmation during the procedure. All biopsy samples were successfully obtained on the first pass without complications, and pathology confirmed high\u2010grade B\u2010cell lymphoma. This case highlights the feasibility and clinical utility of deploying AR\u2010guided interventions in outpatient procedure rooms, supporting broader adoption of AR technologies in settings beyond the operating room or angiography suite.<\/jats:p>","DOI":"10.1002\/ccr3.71850","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T04:50:36Z","timestamp":1768798236000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Augmented Reality Visualization and Navigation Operationalized in Biopsy of Indeterminate Splenic Mass"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4881-3812","authenticated-orcid":false,"given":"Alexander S.","family":"Misono","sequence":"first","affiliation":[{"name":"Hoag Memorial Hospital Presbyterian Department of Radiology, Division of Interventional Radiology  Newport Beach California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,18]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1089\/end.2013.0344"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2021.11.014"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.JMI.11.6.062602"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.7602\/jmis.2025.28.3.122"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-022-05303-6"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-019-06054-6"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/curroncol28030163"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19106347"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/ons\/opx279"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.33590\/emjradiol\/JMVR8857"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.161.2.3763890"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.3171\/2021.2.SPINE202097"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.25259\/JNRP_454_2024"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2018.01.067"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41747-023-00353-w"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11548-024-03148-5"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.71850","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.71850","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.71850","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T07:19:53Z","timestamp":1769066393000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.71850"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1002\/ccr3.71850"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.71850","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-09-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71850"}}