{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T19:57:33Z","timestamp":1772999853001,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Hypercoiling of the umbilical cord can lead to fetal growth restriction and stillbirth because the cord is vulnerable to blood flow disturbances caused by external forces. A single umbilical artery (SUA) is a relatively common abnormality; however, isolated SUA is associated with fetal growth restriction and stillbirth. We report a case of fetal growth restriction with both SUA and hypercoiling. A 27\u2010year\u2010old primigravida was evaluated at 37\u2009weeks of gestation. Prenatal ultrasonography revealed a small\u2010for\u2010gestational\u2010age fetus with a single umbilical artery and a hypercoiled umbilical cord. Continuous fetal monitoring was initiated upon admission. Cardiotocography demonstrated recurrent prolonged decelerations, necessitating an emergency cesarean section. Placental histopathology revealed fetal vascular malperfusion with hyalinized avascular villi and thrombotic occlusion of one umbilical artery, indicating disturbed fetoplacental circulation likely related to SUA and hypercoiling. The coexistence of hypercoiling and a single umbilical artery was associated with the risk of fetal vascular malperfusion and growth restriction. Careful antenatal surveillance and timely delivery are essential to prevent adverse perinatal outcomes in multiple umbilical cord anomalies.<\/jats:p>","DOI":"10.1002\/ccr3.71862","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T06:24:02Z","timestamp":1770186242000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hypercoiling and Single Umbilical Artery Associated With Fetal Placental Malperfusion and Growth Restriction: A Case Report"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-7239-5552","authenticated-orcid":false,"given":"Masaya","family":"Tanimura","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Toyooka Hospital  Toyooka Hyogo Japan"},{"name":"Department of Experimental Genome Research Research Institute for Microbial Diseases, Osaka University  Suita Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3287-8092","authenticated-orcid":false,"given":"Tomo","family":"Yamagata","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Toyooka Hospital  Toyooka Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moyu","family":"Matsui","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Toyooka Hospital  Toyooka Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Yamaoka","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Toyooka Hospital  Toyooka Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7909-3143","authenticated-orcid":false,"given":"Kohei","family":"Ida","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Toyooka Hospital  Toyooka Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shohei","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Toyooka Hospital  Toyooka Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6261-2219","authenticated-orcid":false,"given":"Miyu","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Toyooka Hospital  Toyooka Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1747-2401","authenticated-orcid":false,"given":"Motonori","family":"Matsubara","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Toyooka Hospital  Toyooka Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,3]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2019.1594187"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100029\u20101241732"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181841395"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000006049"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2016.09.004"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1515\/jpm\u20102021\u20100260"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2015\u20100225\u2010CC"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/apm.12849"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.2350\/12\u201006\u20101211\u2010OA.1"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/sci6040065"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.29237"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000209197.84185.15"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.71862","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.71862","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.71862","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T17:24:12Z","timestamp":1772990652000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.71862"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1002\/ccr3.71862"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.71862","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"2025-11-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71862"}}