{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T20:24:05Z","timestamp":1778099045673,"version":"3.51.4"},"reference-count":10,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T00:00:00Z","timestamp":1684195200000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000848","name":"University of Edinburgh","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000848","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Papillary thyroid carcinoma (PTC) primarily located in the pyramidal lobe of the thyroid gland is extremely rare, therefore the clinical and pathological features are not well understood. The authors describe a case of PTC of the pyramidal lobe, in a 77\u2010year\u2010old woman who underwent en bloc total thyroidectomy with pyramidal lobe, hyoid bone and cervical lymph node excision. In line with the present case, current literature reports a greater presence of worse prognostic factors, namely extrathyroidal extension, advanced T stage or presence of cervical lymph node metastasis. Recently, a new classification has been suggested\u2014Upper Neck Papillary Thyroid Cancer (UPTC)\u2014which encompasses these carcinomas, Delphi ganglion metastases and thyroglossal duct cyst carcinomas, with potential clinical and therapeutic implications, particularly the need for orthotopic thyroidectomy. Also, the complete excision of the pyramidal lobe during thyroidectomy may influence the success of radioactive iodine therapy and the patient's follow\u2010up surveillance.<\/jats:p>","DOI":"10.1002\/ccr3.7189","type":"journal-article","created":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T03:58:52Z","timestamp":1684295932000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Pyramidal lobe\u2010dominant papillary thyroid carcinoma\u2014A rare entity with important clinical implications"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8349-8857","authenticated-orcid":false,"given":"Henrique","family":"Messias","sequence":"first","affiliation":[{"name":"Head and Neck Surgery Department Portuguese Institute of Oncology Francisco Gentil  Lisbon Portugal"},{"name":"Division of Health Sciences University of Edinburgh  Edinburgh UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Lu\u00edsa","family":"Sequeira","sequence":"additional","affiliation":[{"name":"Head and Neck Surgery Department Portuguese Institute of Oncology Francisco Gentil  Lisbon Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo","family":"Nogueira","sequence":"additional","affiliation":[{"name":"Head and Neck Surgery Department Portuguese Institute of Oncology Francisco Gentil  Lisbon Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Zagalo","sequence":"additional","affiliation":[{"name":"Head and Neck Surgery Department Portuguese Institute of Oncology Francisco Gentil  Lisbon Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariluz","family":"Martins","sequence":"additional","affiliation":[{"name":"Head and Neck Surgery Department Portuguese Institute of Oncology Francisco Gentil  Lisbon Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Gomes","sequence":"additional","affiliation":[{"name":"Head and Neck Surgery Department Portuguese Institute of Oncology Francisco Gentil  Lisbon Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,5,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00276-006-0165-1"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.EJ13-0316"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.4174\/astr.2017.92.3.123"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13092253"},{"key":"e_1_2_10_6_1","first-page":"52","article-title":"Recurrence of papillary thyroid cancer after optimized surgery","volume":"4","author":"Grant CS","year":"2015","journal-title":"Gland Surg"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.23967"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000015210"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25824"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25295"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000430894"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.7189","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T08:44:23Z","timestamp":1692434663000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.7189"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["10.1002\/ccr3.7189"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.7189","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"2023-02-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e7189"}}