{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T23:37:34Z","timestamp":1769125054066,"version":"3.49.0"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:00:00Z","timestamp":1768867200000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Primary Non\u2010Hodgkin's lymphoma of the breast is rare, accounting for &lt;\u20090.5% of breast cancers and ~2% of extranodal lymphomas. It often presents as a painless lump, mimicking carcinoma and complicating diagnosis. Case PresentationWe report a 65\u2010year\u2010old post\u2010menopausal, hypertensive, and diabetic woman with a gradually enlarging left breast mass. Imaging revealed a suspicious lesion. Core biopsy suggested poorly differentiated carcinoma, but immunohistochemistry confirmed diffuse large B\u2010cell lymphoma (DLBCL), activated B\u2010cell subtype, with high Ki\u201067 (~90%). PET\/CT showed localized disease. She received six cycles of CHOP chemotherapy, with rituximab added from the second cycle. Treatment was well tolerated. Follow\u2010up PET\/CT and biopsy demonstrated complete metabolic and pathological remission. ConclusionPrimary breast DLBCL is rare and easily misdiagnosed as carcinoma. Immunohistochemistry is therefore crucial for correct diagnosis. R\u2010CHOP chemoimmunotherapy is the cornerstone of treatment.<\/jats:p>","DOI":"10.1002\/ccr3.71891","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T12:43:34Z","timestamp":1768913014000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Rarity to Remission: Complete Response of Primary Breast Diffuse Large B\u2010Cell Lymphoma With Chemoimmunotherapy"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-3855-450X","authenticated-orcid":false,"given":"Abhisek","family":"Jha","sequence":"first","affiliation":[{"name":"Department of Clinical Oncology Birat Medical College and Teaching Hospital (BMCTH)  Morang Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4370-5273","authenticated-orcid":false,"given":"Vivek","family":"Ghosh","sequence":"additional","affiliation":[{"name":"Department of Clinical Oncology Birat Medical College and Teaching Hospital (BMCTH)  Morang Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9963-7481","authenticated-orcid":false,"given":"Shristi","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Clinical Oncology Birat Medical College and Teaching Hospital (BMCTH)  Morang Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samana","family":"Oli","sequence":"additional","affiliation":[{"name":"Department of Clinical Oncology Birat Medical College and Teaching Hospital (BMCTH)  Morang Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asmita","family":"Rayamajhi","sequence":"additional","affiliation":[{"name":"Department of Clinical Oncology Birat Medical College and Teaching Hospital (BMCTH)  Morang Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dhiraj","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Clinical Oncology Birat Medical College and Teaching Hospital (BMCTH)  Morang Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1426-9345","authenticated-orcid":false,"given":"Anish","family":"Luitel","sequence":"additional","affiliation":[{"name":"Department of Clinical Oncology Birat Medical College and Teaching Hospital (BMCTH)  Morang Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barun","family":"Khanal","sequence":"additional","affiliation":[{"name":"Department of Clinical Oncology Birat Medical College and Teaching Hospital (BMCTH)  Morang Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aabish","family":"Dahal","sequence":"additional","affiliation":[{"name":"Department of Clinical Oncology Birat Medical College and Teaching Hospital (BMCTH)  Morang Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarada","family":"Khadka","sequence":"additional","affiliation":[{"name":"Department of Breast &amp; Endocrine Surgery BP Koirala Institute of Health Sciences (BPKIHS)  Dharan Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,20]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2022.103310"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ehpc.2016.07.004"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radcr.2018.04.009"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/78413721"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpra.2022.01.004"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097\u20100142(197206)29:6<1705::AID\u2010CNCR2820290640>3.0.CO;2\u2010I"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radcr.2020.10.039"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.2019180097"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2015.02.002"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2020.12393"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdt181"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13256\u2010023\u201003998\u20108"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.21037\/tcr.2017.11.10"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(19)33008\u20109"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00066\u2010018\u20101378\u2010z"},{"key":"e_1_2_14_17_1","volume-title":"StatPearls","author":"Hufnagle J. 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