{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T11:37:03Z","timestamp":1788089823633,"version":"build-2803163510"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T00:00:00Z","timestamp":1768953600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T00:00:00Z","timestamp":1768953600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Balancing the cerebrovascular benefits of low\u2010dose aspirin (LDA) with its significant gastrointestinal (GI) bleeding risk is a critical challenge in secondary stroke prevention. We describe a cautionary case of a 60\u2010year\u2010old male who, 6\u2009months after starting LDA for a transient ischemic attack (TIA), presented with a life\u2010threatening upper GI bleed. The patient had not been prescribed a prophylactic proton pump inhibitor (PPI). Investigations revealed a hemoglobin of 9.6\u2009g\/dL and multiple gastric ulcers on endoscopy, with negative testing for\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Helicobacter pylori<\/jats:italic>\n                    <\/jats:styled-content>\n                    . This case of a preventable, severe adverse event serves as a stark reminder that guideline\u2010recommended gastroprotection is not optional but essential. Systematic risk assessment and PPI co\u2010prescription in at\u2010risk individuals are imperative for the safe and effective use of long\u2010term antiplatelet therapy.\n                  <\/jats:p>","DOI":"10.1002\/ccr3.71913","type":"journal-article","created":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T04:29:26Z","timestamp":1769056166000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Low\u2010Dose Aspirin Induced Gastric Ulcer in a Patient With\n                    <scp>TIA<\/scp>\n                    : A Clinical Caution for Aspirin Therapy Without Gastroprotection"],"prefix":"10.1002","volume":"14","author":[{"given":"Kainat","family":"Husain","sequence":"first","affiliation":[{"name":"Jawaharlal Nehru Medical College  Aligarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Bannu Medical College  Bannu Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fazeela","family":"Bibi","sequence":"additional","affiliation":[{"name":"Jinnah Medical and Dental College  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalil","family":"El Abdi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Pharmacy of Rabat Mohammed V University  Rabat Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bilal","family":"Aslam","sequence":"additional","affiliation":[{"name":"University of Lahore  Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah","family":"Saud","sequence":"additional","affiliation":[{"name":"Gajju Khan Medical College  Swabi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vohra","family":"Maham Hassan","sequence":"additional","affiliation":[{"name":"Jinnah Medical and Dental College  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aminullah","family":"Betanai","sequence":"additional","affiliation":[{"name":"Holy Family Hospital Rawalpindi  Rawalpindi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Muneeb","sequence":"additional","affiliation":[{"name":"Khyber Medical College  Peshawar Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7885-6214","authenticated-orcid":false,"given":"Said Hamid","family":"Sadat","sequence":"additional","affiliation":[{"name":"Kabul University of Medical Sciences Abu Ali Ibn Sina  Kabul Afghanistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,21]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2023.102028"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejro.2023.100527"},{"issue":"3","key":"e_1_2_13_4_1","first-page":"1","article-title":"Is Transient Ischemic Attack a Medical Emergency? 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