{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T19:56:17Z","timestamp":1772999777190,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T00:00:00Z","timestamp":1769558400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T00:00:00Z","timestamp":1769558400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Extensive hepatic infarction is a rare but potentially fatal complication of HELLP syndrome and is often difficult to recognize because of nonspecific clinical manifestations. A 34\u2010year\u2010old woman developed HELLP syndrome shortly after cesarean delivery for severe pre\u2010eclampsia, presenting with oliguria, marked thrombocytopenia (50\u2009\u00d7\u200910\n                    <jats:sup>9<\/jats:sup>\n                    \/L), and rapidly rising transaminases (ALT 1077\u2009U\/L, AST 1280\u2009U\/L). Contrast\u2010enhanced computed tomography (CT) revealed extensive hepatic infarction. Laboratory findings demonstrated microangiopathic hemolysis, severe coagulopathy, and acute kidney injury. Transient elevation of the terminal complement complex C5b\u20109 raised concern for atypical hemolytic uremic syndrome. The patient was treated with plasma exchange, corticosteroids, organ support, and individualized anticoagulation guided by bleeding risk assessment. Serial follow\u2010up demonstrated sustained hematologic, renal, and hepatic recovery, ultimately excluding atypical hemolytic uremic syndrome. This case highlights the importance of imaging\u2010guided diagnosis, dynamic laboratory evaluation, and individualized therapeutic decision\u2010making in HELLP syndrome complicated by severe hepatic injury.\n                  <\/jats:p>","DOI":"10.1002\/ccr3.71953","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T04:53:53Z","timestamp":1769662433000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Case of Severe Pre\u2010Eclampsia Complicated by\n                    <scp>HELLP<\/scp>\n                    Syndrome and Extensive Hepatic Infarction"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-5616-436X","authenticated-orcid":false,"given":"Tiange","family":"Xia","sequence":"first","affiliation":[{"name":"Nanjing University of Chinese Medicine  Nanjing China"},{"name":"Wuxi TCM Hospital Affiliated to Nanjing University of Chinese Medicine  Wuxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fei","family":"Gao","sequence":"additional","affiliation":[{"name":"Wuxi People's Hospital  Wuxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fengming","family":"Liang","sequence":"additional","affiliation":[{"name":"Wuxi People's Hospital  Wuxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Shao","sequence":"additional","affiliation":[{"name":"Wuxi TCM Hospital Affiliated to Nanjing University of Chinese Medicine  Wuxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,28]]},"reference":[{"issue":"1","key":"e_1_2_12_2_1","first-page":"6","article-title":"What Affects the Outcome of Severe Preeclampsia?","volume":"10","author":"Elve\u0111i\u2010Ga\u0161parovi\u0107 V.","year":"2015","journal-title":"Signa Vitae"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/nure.12055"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000126245.35811.2a"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.08.014"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tjog.2012.07.018"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(90)90376-I"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(16)32330-4"},{"issue":"12","key":"e_1_2_12_9_1","first-page":"1138","article-title":"Liver Disease in Toxemia of Pregnancy","volume":"81","author":"Rolfes D. 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