{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T01:10:17Z","timestamp":1774314617493,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T00:00:00Z","timestamp":1770336000000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Olanzapine, an atypical antipsychotic widely used for psychiatric disorders, is typically associated with tachycardia and QT prolongation in overdose, while bradycardia remains a rare and underrecognized effect. We report a 20\u2010year\u2010old woman with major depressive disorder who presented 4\u2009h after ingesting 100\u2009mg of olanzapine in a suicide attempt. She exhibited marked sinus bradycardia (41\u2009bpm) with stable hemodynamics and no QT prolongation. Laboratory and toxicology results were unremarkable. Supportive care, including oxygen, fluids, and cardiac monitoring, led to complete recovery within 48\u2009h. This case highlights isolated bradycardia as an uncommon but important manifestation of olanzapine toxicity. Clinicians should consider bradycardia in the cardiovascular spectrum of olanzapine overdose and ensure vigilant monitoring to prevent potential complications.<\/jats:p>","DOI":"10.1002\/ccr3.71987","type":"journal-article","created":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T05:59:16Z","timestamp":1770443956000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Olanzapine Overdose\u2014Induced Bradycardia in a Young Adult With Major Depressive Disorder: A Case Report and Literature Review"],"prefix":"10.1002","volume":"14","author":[{"given":"Mohammad Ghasemi","family":"Palangi","sequence":"first","affiliation":[{"name":"Department of Cardiology, School of Medicine, Ayatollah Mousavi Hospital Zanjan University of Medical Science  Zanjan Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan","family":"Ahangar","sequence":"additional","affiliation":[{"name":"Department of Cardiology, School of Medicine, Ayatollah Mousavi Hospital Zanjan University of Medical Science  Zanjan Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nona","family":"Sakhaie","sequence":"additional","affiliation":[{"name":"School of Medicine, Ayatollah Mousavi Hospital Zanjan University of Medical Science  Zanjan Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4366-649X","authenticated-orcid":false,"given":"Payman","family":"Yasami","sequence":"additional","affiliation":[{"name":"Student Research Committee, Department of Cardiology, School of Medicine Zanjan University of Medical Science  Zanjan Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,6]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.65279"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1988.01800330013001"},{"issue":"12","key":"e_1_2_15_4_1","first-page":"5","article-title":"The Expert Consensus Guideline Series. Optimizing Pharmacologic Treatment of Psychotic Disorders. Introduction: Methods, Commentary, and Summary","volume":"64","author":"Kane J. 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