{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T19:57:44Z","timestamp":1772999864375,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T00:00:00Z","timestamp":1770163200000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Methanol toxicity is an emergency that doctors come across all around the globe, requiring immediate treatment or it can cause life\u2010threatening conditions affecting the central nervous system, causing toxic optic neuropathy and metabolic acidosis. We present a case of an 18\u2010year\u2010old boy, who presented in the medicine emergency with sudden bilateral visual loss and vomiting. He did not have any significant past medical history and all of his examinations were normal except bilaterally dilated pupils and the fundus examination showing bilateral optic disc pallor and cup to disc (C\/D) ratio 0.5 and his visual acuity was no perception of light (NPL). He was admitted and treated conservatively with high\u2010dose steroids and ethanol. Later on, a diagnosis of methanol toxicity was made based on toxicology report and imaging studies. His ABGs remained normal throughout and his vision improved to hand movement (HM) over the course of 2\u2009weeks. Methanol toxicity can vary in presentation and could lead to toxic optic neuropathy causing sudden total visual loss. It usually occurs as an outbreak so cases like these should be reported to have a general awareness about it; aiding in early detection, timely management and better public health strategies.<\/jats:p>","DOI":"10.1002\/ccr3.71989","type":"journal-article","created":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T04:27:10Z","timestamp":1770265630000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Methanol Induced Optic Neuropathy: An Unusual Case With the Absence of Classic Symptoms"],"prefix":"10.1002","volume":"14","author":[{"given":"Humza","family":"Tariq","sequence":"first","affiliation":[{"name":"Lahore General Hospital  Lahore Punjab Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Gohar","sequence":"additional","affiliation":[{"name":"Lahore General Hospital  Lahore Punjab Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-5248-0749","authenticated-orcid":false,"given":"Muhammad Husnain","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Department of Medicine Tentishev Satkynbai Memorial Asian Medical Institute  Kant Kyrgyzstan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad Huzaifa","family":"Ameer","sequence":"additional","affiliation":[{"name":"Lahore General Hospital  Lahore Punjab Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-8599-6861","authenticated-orcid":false,"given":"Masab","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Medicine Punjab Medical College  Faisalabad Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asad Ullah","family":"Ansari","sequence":"additional","affiliation":[{"name":"Lahore General Hospital  Lahore Punjab Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rehan Naseer","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Department of Medicine King Edward Medical University  Lahore Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,4]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnen\/nlae030"},{"issue":"2","key":"e_1_2_13_3_1","first-page":"436","article-title":"Causation or Coincidence? A Case of Methanol Intoxication Presenting With Acute Myocardial Infarction and Visual Impairment","volume":"41","author":"Boyaci F.","year":"2024","journal-title":"Journal of Experimental and Clinical Medicine"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s42269\u2010023\u201001092\u2010z"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.55519\/JAMC-02-13166"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11419\u2010023\u201000680\u2010y"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2024.02.1199"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/08820538.2024.2358310"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.30574\/wjarr.2024.22.2.1580"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-66481-4"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12873-024-00976-1"},{"key":"e_1_2_13_12_1","first-page":"97","article-title":"Efficacy of High\u2010Dose Intravenous Steroid Treatment in Methanol\u2010Induced Optic Neuropathy: A Systematic Review","volume":"11","author":"Permaisuari N.","year":"2019","journal-title":"International Journal of Applied Pharmaceutics"},{"issue":"1","key":"e_1_2_13_13_1","first-page":"14","article-title":"Methanol Toxic Optic Neuropathy (Characteristic and Evaluation of Therapy)","volume":"42","author":"Yunard A.","year":"2016","journal-title":"Ophthalmologica Indonesiana"},{"key":"e_1_2_13_14_1","volume-title":"StatPearls","author":"Ashurst J. 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