{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T19:56:26Z","timestamp":1772999786003,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T00:00:00Z","timestamp":1770249600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Klebsiella pneumoniae<\/jats:italic>\n                    <\/jats:styled-content>\n                    is an uncommon but increasingly recognized cause of Lemierre's syndrome, a condition classically associated with\n                    <jats:italic>\n                      <jats:styled-content style=\"fixed-case\">Fusobacterium necrophorum<\/jats:styled-content>\n                      .\n                    <\/jats:italic>\n                    This report describes a 32\u2010year\u2010old woman with poorly controlled type 2 diabetes mellitus who presented with a progressive odontogenic infection complicated by internal jugular vein thrombosis and cavitary septic pulmonary emboli. Imaging demonstrated a deep neck abscess with adjacent thrombophlebitis, and cultures from surgical drainage yielded\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>K. pneumoniae<\/jats:italic>\n                    <\/jats:styled-content>\n                    with a wild\u2010type susceptibility profile. The patient required invasive mechanical ventilation, broad\u2010spectrum antibiotics, surgical source control, and therapeutic anticoagulation, resulting in complete clinical recovery. A review of published cases from 1996 to 2025 was performed, highlighting diabetes as the predominant risk factor, odontogenic or oropharyngeal disease as the most common source, and septic pulmonary emboli as a hallmark manifestation. This case represents the second documented instance of\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>K. pneumoniae<\/jats:italic>\n                    <\/jats:styled-content>\n                    \u2013associated Lemierre's syndrome in Nicaragua and reinforces the need for early imaging, prompt surgical management, and targeted antimicrobial therapy in diabetic patients presenting with deep neck infections.\n                  <\/jats:p>","DOI":"10.1002\/ccr3.72003","type":"journal-article","created":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T03:59:33Z","timestamp":1770350373000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Lemierre's Syndrome Caused by\n                    <i>Klebsiella pneumoniae<\/i>\n                    : Case Report and Review of the Literature"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-0436-9704","authenticated-orcid":false,"given":"Abril Aguilar","family":"Guerrero","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Hospital Escuela Manolo Morales Peralta  Managua Nicaragua"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2589-8497","authenticated-orcid":false,"given":"Eduardo Porras","family":"Rosales","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Hospital Escuela Manolo Morales Peralta  Managua Nicaragua"},{"name":"Infectious Diseases Service Hospital Escuela Manolo Morales Peralta  Managua Nicaragua"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,5]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.43685"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473\u20103099(12)70089\u20100"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00019048-199608000-00010"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2012.03.012"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/1752\u20101947\u20106\u201097"},{"issue":"8","key":"e_1_2_12_7_1","first-page":"276","article-title":"Lemierre's Syndrome Caused by Klebsiella pneumoniae in a Diabetic Patient: A Case Report and Literature Review","volume":"74","author":"Chuncharunee A.","year":"2015","journal-title":"Hawaii Journal of Medicine & Public 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