{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T22:25:23Z","timestamp":1791411923853,"version":"4.3.3"},"reference-count":9,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T00:00:00Z","timestamp":1771200000000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Mesalazine is widely used in the management of ulcerative colitis and is generally well tolerated. Rarely, it can cause eosinophilic pneumonitis, a potentially serious form of drug\u2010induced lung injury that often mimics infection. We report a 24\u2010year\u2010old male with longstanding ulcerative colitis on mesalazine therapy for 2\u2009years and 4\u2009months who presented with progressive dyspnea and non\u2010resolving pulmonary infiltrates. Despite empirical antibiotic therapy, his respiratory symptoms worsened. Investigations revealed marked peripheral eosinophilia and bilateral subpleural ground\u2010glass opacities on CT imaging. Mesalazine\u2010induced eosinophilic pneumonitis was suspected. Drug withdrawal and systemic corticosteroid therapy resulted in rapid clinical and radiological improvement. This case highlights that mesalazine\u2010related pulmonary toxicity may occur even after prolonged stable therapy and should be considered in patients with ulcerative colitis presenting with unexplained or non\u2010resolving respiratory symptoms.<\/jats:p>","DOI":"10.1002\/ccr3.72029","type":"journal-article","created":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T04:33:23Z","timestamp":1771302803000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Late\u2010Onset Mesalazine\u2010Induced Eosinophilic Pneumonitis Presenting as Non\u2010Resolving Pneumonia: A Diagnostic Pitfall in Ulcerative Colitis"],"prefix":"10.1002","volume":"14","author":[{"given":"Siraj","family":"Nasim","sequence":"first","affiliation":[{"name":"Acute Medicine Department Queen Elizabeth the Queen Mother Hospital  Margate UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1556-5795","authenticated-orcid":false,"given":"Tamer Mohamed","family":"Zaalouk","sequence":"additional","affiliation":[{"name":"Acute Medicine Department Queen Elizabeth the Queen Mother Hospital  Margate UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abu","family":"Bocus","sequence":"additional","affiliation":[{"name":"Acute Medicine Department Queen Elizabeth the Queen Mother Hospital  Margate UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maged","family":"Kerols","sequence":"additional","affiliation":[{"name":"Acute Medicine Department Queen Elizabeth the Queen Mother Hospital  Margate UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,16]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2011.67"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.126.5.1703"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.15.3183"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/0022\u20103859.65288"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.01.00271201"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2021.01.030"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.7861\/clinmed.2021\u20100434"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00054725\u2010200303000\u201000002"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.20.5.g00se181245"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.72029","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.72029","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.72029","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T17:24:45Z","timestamp":1772990685000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.72029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1002\/ccr3.72029"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.72029","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"2025-11-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-31","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e72029"}}