{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T19:57:40Z","timestamp":1772999860953,"version":"3.50.1"},"reference-count":11,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T00:00:00Z","timestamp":1770940800000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Rheumatic symptoms can be associated with malignancies. Although sacroiliitis is not a classic paraneoplastic syndrome, malignant infiltration of sacroiliac joints by multiple myeloma can mimic inflammatory rheumatologic disease. Multiple myeloma (MM), a plasma cell malignancy often presenting with bone pain, can involve axial skeletal structures, including the sacroiliac joints. We report a 40\u2010year\u2010old male with chronic low back pain and bilateral ankle enthesitis, unresponsive to nonsteroidal anti\u2010inflammatory drugs (NSAIDs), along with systemic symptoms. Initial HLA\u2010B27 positivity and imaging suggested Spondyloarthritis (SpA), but a poor treatment response prompted further evaluation. Serum protein electrophoresis, immunofixation, and bone marrow biopsy confirmed IgG\u2010kappa MM. The coexistence of HLA\u2010B27 positivity and sacroiliac joint changes mimicking axial spondyloarthritis poses a significant diagnostic pitfall, underscoring the need to consider multiple myeloma in patients with atypical features or a poor response to standard rheumatologic therapy.<\/jats:p>","DOI":"10.1002\/ccr3.72038","type":"journal-article","created":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T09:00:17Z","timestamp":1770973217000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Art of Deception: Multiple Myeloma Imitating Spondyloarthritis\u2014A Case Report"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4220-6459","authenticated-orcid":false,"given":"Prabin","family":"Khatri","sequence":"first","affiliation":[{"name":"Department of Rheumatology and Clinical Immunology Kathmandu Medical College  Kathmandu Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aabishkar","family":"Subedi","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Clinical Immunology Kathmandu Medical College  Kathmandu Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bishad","family":"Dahal","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Clinical Immunology Kathmandu Medical College  Kathmandu Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gibson","family":"Shrestha","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Clinical Immunology Kathmandu Medical College  Kathmandu Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9752-5141","authenticated-orcid":false,"given":"Mandish","family":"Phuyal","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Clinical Immunology Kathmandu Medical College  Kathmandu Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9999-7112","authenticated-orcid":false,"given":"Raj","family":"Adhikari","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Clinical Immunology Kathmandu Medical College  Kathmandu Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,13]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.27422"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells14161263"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2023.283784"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.4081\/hr.2017.6887"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keae065"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330\u2010023\u201010463\u20106"},{"issue":"5","key":"e_1_2_14_8_1","first-page":"858","article-title":"Amyloid Arthropathy in Multiple Myeloma: A Comparative Study With Seronegative Rheumatoid Arthritis","volume":"22","author":"Pineda C.","year":"1995","journal-title":"Journal of 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