{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T07:55:27Z","timestamp":1774511727730,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Hydatid disease, caused by various Echinococcus species, is endemic in developing countries and most commonly affects the liver and lungs. Approximately 7.4% of cases involve intrathoracic extrapulmonary locations, with pleural involvement usually resulting from rupture of adjacent hepatic or pulmonary cysts. However, primary pleural hydatid cysts are extremely rare, representing less than 1% of extrapulmonary cases, and may cause compressive symptoms depending on size and location. Diagnosis is guided by serologic testing and imaging, while surgical excision remains the mainstay of treatment. A 26\u2010year\u2010old Middle Eastern female presented to the emergency department with exertional dyspnea, right\u2010sided pleuritic chest pain, low\u2010grade fever, and night sweats. Physical examination revealed decreased breath sounds, dullness to percussion, and increased tactile fremitus on the right side, while imaging confirmed a moderate\u2010to\u2010large right pleural effusion with adhesions and fibrinous strands. Laboratory tests showed a lymphocytic exudative effusion with elevated adenosine deaminase, initially suggesting tuberculous pleuritis. However, negative cultures and positive anti\u2010Echinococcus antibodies redirected the diagnosis to hydatid disease. Video\u2010assisted thoracoscopic surgery (VATS) revealed dense adhesions and granulomatous inflammation on biopsy. Due to restricted lung expansion, right thoracotomy was performed, excising a cystic mass from the mediastinal pleura. Histopathology confirmed a hydatid cyst. The patient recovered well and was discharged on oral Albendazole. This case emphasizes the rarity of primary pleural hydatid cysts, the diagnostic challenges they pose, and the importance of considering parasitic infections in pleural effusions for timely surgical and medical management.<\/jats:p>","DOI":"10.1002\/ccr3.72156","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T11:32:54Z","timestamp":1772969574000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Primary Mediastinal Pleural Hydatid Cyst Mimicking Tuberculous Pleuritis: A Case Report"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-6002-9032","authenticated-orcid":false,"given":"Grace","family":"Tannous","sequence":"first","affiliation":[{"name":"Faculty of Medicine Damascus University  Damascus Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3563-4103","authenticated-orcid":false,"given":"Omar","family":"Al Ayoubi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Damascus University  Damascus Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-1999-6151","authenticated-orcid":false,"given":"Alaa","family":"Senjab","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Damascus University  Damascus Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Abd Alrahman","family":"Saif","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Department Damascus University, Al Mouwasat University Hospital  Damascus Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"hesso","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Department Damascus University, Al Mouwasat University Hospital  Damascus Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Akram","family":"Flioun","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Department Damascus University, Al Mouwasat University Hospital  Damascus Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bassam","family":"Darwish","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Department Damascus University, Al Mouwasat University Hospital  Damascus Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,26]]},"reference":[{"issue":"2","key":"e_1_2_15_2_1","first-page":"166","article-title":"A Primary Pleural Hydatid Cyst in an Unusual Location","volume":"16","author":"Mardani P.","year":"2017","journal-title":"Tanaffos"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.20.3.g00ma06795"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1067\/mtc.2002.119341"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2019.07.31"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.5090\/jcs.22.137"},{"issue":"3","key":"e_1_2_15_7_1","first-page":"230","article-title":"Primary Intrathoracic Extrapulmonary Hydatid Cysts: Analysis of 14 Patients With a Rare Clinical Entity","volume":"36","author":"Gursoy S.","year":"2009","journal-title":"Texas Heart Institute Journal"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v8.i7.1203"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0008114"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003\u20104975(97)00521\u20103"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.5114\/kitp.2021.105192"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina56110567"},{"key":"e_1_2_15_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13019\u2010023\u201002115\u20106"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.2147\/OAEM.S29942"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.124.3.978"},{"key":"e_1_2_15_16_1","doi-asserted-by":"publisher","DOI":"10.6061\/clinics\/2016(05)05"},{"key":"e_1_2_15_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2008.03.037"},{"key":"e_1_2_15_18_1","doi-asserted-by":"publisher","DOI":"10.5152\/TurkThoracJ.2018.18133"},{"key":"e_1_2_15_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00408-009-9165-3"},{"key":"e_1_2_15_20_1","volume-title":"Pleural Diseases","author":"Light R. 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