{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T16:34:59Z","timestamp":1775493299775,"version":"3.50.1"},"reference-count":11,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,4,16]],"date-time":"2023-04-16T00:00:00Z","timestamp":1681603200000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>High\u2010grade myofibroblastic sarcoma is a rare mesenchymal tumor with a high recurrence and metastatic rate. Few cases of high\u2010grade myofibroblastic sarcomas have been reported. Herein, we report a rare case of undifferentiated, high\u2010grade myofibroblastic sarcoma with an unclear primary site, initially presenting with oral symptoms. High\u2010grade myofibroblastic sarcoma was diagnosed following an excisional biopsy of a gingival tumor. After this excisional biopsy, systemic imaging revealed multiple metastases in the tonsil, lung, liver, kidney, and eye. The patient underwent two cycles of chemotherapy (doxorubicin). During follow\u2010up, the tumor progressed rapidly and metastasized to the skin of the head and neck. The patient expired three months after the initial examination.<\/jats:p>","DOI":"10.1002\/ccr3.7218","type":"journal-article","created":{"date-parts":[[2023,4,17]],"date-time":"2023-04-17T01:45:45Z","timestamp":1681695945000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A unique case of high\u2010grade myofibroblastic sarcoma initially presenting with oral symptoms"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6437-8614","authenticated-orcid":false,"given":"Takeshi","family":"Harada","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Kansai Rosai Hospital  Amagasaki Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Togawa","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Kansai Rosai Hospital  Amagasaki Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Miyamoto","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Kansai Rosai Hospital  Amagasaki Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaka","family":"Matsushita","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Kansai Rosai Hospital  Amagasaki Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukimasa","family":"Hatachi","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Kansai Rosai Hospital  Amagasaki Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,4,16]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199810000-00008"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v23.i38.7054"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/1759-7714.13613"},{"key":"e_1_2_12_5_1","first-page":"15","volume-title":"WHO Classification of Tumors of Soft Tissue and Bone","author":"Fletcher CD","year":"2013"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.2350\/10-12-0944-PB.1"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pap.0000131773.16130.aa"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAT.0000000000000048"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.2006.02068.x"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-013-1494-1"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.72.337"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(14)70063-4"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.7218","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T14:01:18Z","timestamp":1764252078000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.7218"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.1002\/ccr3.7218"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.7218","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"2023-03-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e7218"}}