{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T14:05:03Z","timestamp":1764252303398,"version":"3.46.0"},"reference-count":16,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T00:00:00Z","timestamp":1682121600000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Pain is common in the acute phase of Guillain\u2013Barr\u00e9 Syndrome and can be severe and refractory. Pain in GBS may not always respond to contemporary pain therapy. An epidural can potentially be considered for the treatment of refractory pain after a careful patient\u2010centered discussion with the patient about risks.<\/jats:p>","DOI":"10.1002\/ccr3.7221","type":"journal-article","created":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T23:44:15Z","timestamp":1682207055000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Bupivacaine and morphine epidural use for refractory neuropathic pain relief in a\n                    <scp>Guillain\u2013Barr\u00e9<\/scp>\n                    syndrome patient"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0453-1047","authenticated-orcid":false,"given":"Eudiet","family":"Trollip","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine University of Alberta  Edmonton Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Hawkins","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine University of Alberta  Edmonton Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"Kwek","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine Grey Nuns Hospital  Edmonton Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krista","family":"Dewart","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine Grey Nuns Hospital  Edmonton Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehvash","family":"Qureshi","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine Grey Nuns Hospital  Edmonton Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janek Manoj","family":"Senaratne","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine Grey Nuns Hospital  Edmonton Alberta Canada"},{"name":"Department of Critical Care Medicine University of Alberta  Edmonton Alberta Canada"},{"name":"Department of Medicine, Division of Cardiology University of Alberta  Edmonton Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,4,22]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000011595"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199111000-00030"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181f88345"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nrleng.2014.04.01"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.52.8.999"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(94)90068-X"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.62.8.1194"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.46747\/cfp.6803179"},{"issue":"1","key":"e_1_2_12_10_1","first-page":"35","article-title":"Guillain\u2010Barr\u00e9 syndrome","volume":"39","author":"Panesar K","year":"2014","journal-title":"Neurology, US Pharm"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200410000-00021"},{"issue":"7","key":"e_1_2_12_12_1","first-page":"1341","article-title":"Spinal Epidural Abscess: a diagnostic challenge","volume":"65","author":"Deardre C","year":"2002","journal-title":"Am Fam Physician"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aew026"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.19080\/JAICM.2017.04.555632"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1986.00520110080023"},{"key":"e_1_2_12_16_1","first-page":"171","article-title":"Epidural fentanyl\u2010bupivacaine infusion for Management of Pain in the Guillain\u2010Barr\u00e9 syndrome","volume":"17","author":"Ali M","year":"1992","journal-title":"Anesthesia and Pain Medicine"},{"key":"e_1_2_12_17_1","article-title":"Pharmacological treatment for pain in Guillain\u2010Barr\u00e9 syndrome","volume":"10","author":"Liu J","year":"2013","journal-title":"Cochrane Database Syst Rev"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.7221","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T14:01:16Z","timestamp":1764252076000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.7221"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.1002\/ccr3.7221"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.7221","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"type":"print","value":"2050-0904"},{"type":"electronic","value":"2050-0904"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"2022-08-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e7221"}}