{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T07:54:03Z","timestamp":1774511643811,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T00:00:00Z","timestamp":1773187200000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Lupus nephritis is a severe manifestation of systemic lupus erythematosus (SLE) typically characterized by glomerular \u201cfull\u2010house\u201d immunofluorescence. However, non\u2010lupus nephropathies may occasionally exhibit similar patterns, creating diagnostic uncertainty. Non\u2010lupus full\u2010house nephropathy (FHN) is a recently recognized entity in which a full\u2010house immunofluorescence pattern occurs in the absence of serological or clinical evidence of SLE. We report a 4\u2010year\u2010old girl who presented with generalized edema, hematuria, hypertension, and nephrotic\u2010range proteinuria. Laboratory evaluation revealed anemia, elevated serum creatinine, and low complement C3 levels but negative antinuclear antibody (ANA) and anti\u2010double\u2010stranded DNA (anti\u2010dsDNA) tests. Renal biopsy demonstrated diffuse proliferative glomerulonephritis consistent with lupus nephritis Class IV, with full\u2010house immunofluorescence positivity for IgG, IgA, IgM, C3, and C1q. In the absence of systemic or serologic lupus features, a diagnosis of non\u2010lupus full\u2010house nephropathy was made. The patient was treated with pulse methylprednisolone followed by oral prednisolone, monthly cyclophosphamide for 6\u2009months, and maintenance therapy with azathioprine and low\u2010dose steroids. Hydroxychloroquine and antihypertensive agents were added. She achieved clinical and biochemical remission on follow\u2010up.<\/jats:p>","DOI":"10.1002\/ccr3.72232","type":"journal-article","created":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T04:02:04Z","timestamp":1773288124000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pediatric Non\u2010Lupus Full House Nephropathy: Case Report and Review of Literature"],"prefix":"10.1002","volume":"14","author":[{"given":"Mohammad Firoz","family":"Anjum","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Patan Academy of Health Sciences  Lalitpur Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suraj","family":"Sah","sequence":"additional","affiliation":[{"name":"Patan Academy of Health Sciences  Lalitpur Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1377-3362","authenticated-orcid":false,"given":"Inesh","family":"Khanal","sequence":"additional","affiliation":[{"name":"Patan Academy of Health Sciences  Lalitpur Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharmila","family":"Gainju","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Patan Academy of Health Sciences  Lalitpur Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sri Ram","family":"K.C.","sequence":"additional","affiliation":[{"name":"Armed Police Force Hospital  Kathmandu Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,11]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/0886022X.2010.510614"},{"issue":"4","key":"e_1_2_9_3_1","article-title":"Pediatric Antinuclear Antibody Negative Full\u2010House Nephropathy: A Clinical Conundrum","volume":"32","author":"Bakar K. B. A.","year":"2022","journal-title":"Iranian Journal of Pediatrics"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/9043003"},{"key":"e_1_2_9_5_1","unstructured":"M.Aringer K.Costenbader D.Daikh et\u00a0al. \u201cEuropean League Against Rheumatism\/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus \u201dArthritis & Rheumatology [Internet] (2019) https:\/\/acrjournals.onlinelibrary.wiley.com\/doi\/10.1002\/art.40930."},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.0000000000000438"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijn.IJN_91_18"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfx020"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.0000000000000438"},{"key":"e_1_2_9_10_1","volume-title":"StatPearls","author":"Musa R.","year":"2025"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.9231"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.12890\/2025_005525"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.4103\/1319-2442.336762"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/14740338.2017.1269168"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.4078\/jrd.2024.0030"},{"key":"e_1_2_9_16_1","unstructured":"R.SadineniandU.Das \u201cClinicopathological Study of Non\u2010Lupus Full\u2010House Nephropathy \u201d[Internet] (accessed 2025 Jun 21) https:\/\/pdfs.semanticscholar.org\/da68\/091709bf8ba5e71ae4d97d48085cbcb720e9.pdf."},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1590\/2175-8239-jbn-2019-0242"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13730-024-00860-8"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/nep.14166"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.72232","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.72232","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.72232","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T06:05:22Z","timestamp":1774505122000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.72232"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1002\/ccr3.72232"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.72232","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"2025-10-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e72232"}}