{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T16:01:39Z","timestamp":1777046499042,"version":"3.51.4"},"reference-count":11,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T00:00:00Z","timestamp":1776988800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T00:00:00Z","timestamp":1776988800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Multiple myeloma (MM) is a malignant hematologic neoplasm that primarily affects the bone marrow and can invade other organs, leading to diverse clinical manifestations. Presentation with gastrointestinal bleeding as the initial symptom is exceptionally rare. We report a case of MM in a 46\u2010year\u2010old man who presented with gastrointestinal bleeding and severe anemia. Routine endoscopic evaluation was inconclusive, but further hematologic and imaging investigations confirmed multiple myeloma. The patient was successfully treated with bortezomib\u2010based chemotherapy and supportive care. This case emphasizes the importance of considering plasma cell dyscrasias in patients with unexplained GI bleeding and anemia, particularly when conventional gastrointestinal causes are excluded.<\/jats:p>","DOI":"10.1002\/ccr3.72340","type":"journal-article","created":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T14:49:26Z","timestamp":1777042166000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Multiple Myeloma Presenting as Lower Gastrointestinal Bleeding: A Case Report"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-1543-8287","authenticated-orcid":false,"given":"Ahmed","family":"Arabi","sequence":"first","affiliation":[{"name":"College of Medicine, QU Health Qatar University  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naseem","family":"Ambra","sequence":"additional","affiliation":[{"name":"College of Medicine, QU Health Qatar University  Doha Qatar"},{"name":"Hamad Medical Corporation  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asgad Mohamed Ahmed","family":"Eltigani","sequence":"additional","affiliation":[{"name":"Hamad Medical Corporation  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asma Ahmed","family":"Yousif","sequence":"additional","affiliation":[{"name":"Hamad Medical Corporation  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdelkarim Hashim","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Hamad Medical Corporation  Doha Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,4,24]]},"reference":[{"key":"e_1_2_12_2_1","first-page":"2405","article-title":"Complicated Gastrointestinal Bleeding of Neoplastic Diseases of the Hematopoietic System","volume":"56","author":"Yoshida T.","year":"1998","journal-title":"Nihon Rinsho"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.8400"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminoncol.2016.11.004"},{"key":"e_1_2_12_5_1","volume-title":"StatPearls","author":"Albagoush S. 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