{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T09:00:26Z","timestamp":1781254826410,"version":"3.54.1"},"reference-count":9,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T00:00:00Z","timestamp":1775952000000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The coexistence of uterine fibroids and gestational hypertension (GH) presents a high\u2010risk obstetric scenario associated with adverse maternal\u2010fetal outcomes. We present the case of a 27\u2010year\u2010old primigravida diagnosed with a 22\u2009\u00d7\u200928\u2009mm anterior uterine fibroid at 8\u2009weeks' gestation, which enlarged to 52\u2009\u00d7\u200948\u2009mm by 29\u2009weeks. At 21\u2009weeks' gestation, she developed new\u2010onset GH (blood pressure 150\/98\u2009mmHg) without proteinuria. Her management included prophylactic low\u2010dose aspirin (75\u2009mg daily), methyldopa (250\u2009mg twice daily), and structured home blood pressure monitoring. When her blood pressure rose to 155\/100\u2009mmHg at 34\u2009weeks, the methyldopa dosage was increased to three times daily, which successfully restored control. Following induction of labor at 40\u2009weeks, the patient had an uncomplicated vaginal delivery of a healthy 3.3\u2009kg neonate with an APGAR score of 9. The postpartum course was unremarkable, and the fibroid regressed significantly. This case illustrated that a proactive, guideline\u2010based strategy uniting early prophylaxis, adaptive pharmacotherapy guided by home monitoring, and anticipatory care can successfully navigate the compounded risks of this clinical dyad, leading to a favorable outcome.<\/jats:p>","DOI":"10.1002\/ccr3.72536","type":"journal-article","created":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T04:50:56Z","timestamp":1776055856000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Proactive Management of Gestational Hypertension in a Patient With Uterine Fibroids: A Case Report"],"prefix":"10.1002","volume":"14","author":[{"given":"Fazeela","family":"Bibi","sequence":"first","affiliation":[{"name":"Jinnah Medical and Dental College  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mala","family":"Jitendra Shahani","sequence":"additional","affiliation":[{"name":"Dow Medical College  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Bannu Medical College  Bannu Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6138-6684","authenticated-orcid":false,"given":"Khalil","family":"Elabdi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Pharmacy of Rabat, Mohammed V University  Rabat Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bilal","family":"Aslam","sequence":"additional","affiliation":[{"name":"University of Lahore  Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barkah","family":"Ali","sequence":"additional","affiliation":[{"name":"Dow Medical College  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Usama","family":"Khan","sequence":"additional","affiliation":[{"name":"Nowshera Medical College  Nowshera Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romaisa","family":"Naveed Akhtar","sequence":"additional","affiliation":[{"name":"Liaquat National Medical College  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazia","family":"Moazzam","sequence":"additional","affiliation":[{"name":"Sir Syed College of Medical Sciences for Girls  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mantasha","family":"Gauhar","sequence":"additional","affiliation":[{"name":"Jinnah Sindh Medical University  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7885-6214","authenticated-orcid":false,"given":"Said Hamid","family":"Sadat","sequence":"additional","affiliation":[{"name":"Kabul University of Medical Science Abu Ali Ibn Sina  Kabul Afghanistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,12]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmw023"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0187821"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYP.0000000000000208"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0000000000002729"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000002709"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.117.10803"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.116.07862"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.19023"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0000000000002777"}],"container-title":["Clinical Case 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