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Giant cell lesions in the oral cavity should prompt investigation for hyperparathyroidism, as early recognition of brown tumors allows appropriate systemic management and may lead to lesion regression after treatment of the endocrine disorder.<\/jats:p>","DOI":"10.1002\/ccr3.72626","type":"journal-article","created":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T04:18:12Z","timestamp":1777436292000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["When an Oral Lesion Uncovers Hyperparathyroidism: A Peripheral Brown Tumor Case"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7678-2588","authenticated-orcid":false,"given":"Bruno Teixeira Gon\u00e7alves","family":"Rodrigues","sequence":"first","affiliation":[{"name":"Oral &amp; Maxillofacial Surgery, Pedro Ernesto University Hospital State University of Rio de Janeiro  Rio de Janeiro Brazil"},{"name":"Department of Oral Medicine Faculdade S\u00e3o Leopoldo Mandic  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-4774-9279","authenticated-orcid":false,"given":"Vanessa Freitas","family":"Pacheco","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine Faculdade S\u00e3o Leopoldo Mandic  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-8118-046X","authenticated-orcid":false,"given":"Livia Xavier Costa do Rego","family":"Moreira","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine Faculdade S\u00e3o Leopoldo Mandic  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4541-2925","authenticated-orcid":false,"given":"Mariana Cartaxo","family":"Faustini","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine Faculdade S\u00e3o Leopoldo Mandic  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3053-0665","authenticated-orcid":false,"given":"Nath\u00e1lia de Almeida","family":"Freire","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine Faculdade S\u00e3o Leopoldo Mandic  Rio de Janeiro Brazil"},{"name":"Oral Medicine, Department of Diagnosis and Therapeutics, Dental School Rio de Janeiro State University  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7629-0698","authenticated-orcid":false,"given":"Danilo Passeado Branco","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Oral &amp; Maxillofacial Surgery, Pedro Ernesto University Hospital State University of Rio de Janeiro  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9234-7903","authenticated-orcid":false,"given":"M\u00f4nica Sim\u00f5es","family":"Israel","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine Faculdade S\u00e3o Leopoldo Mandic  Rio de Janeiro Brazil"},{"name":"Oral Medicine, Department of Diagnosis and Therapeutics, Dental School Rio de Janeiro State University  Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,4,28]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.ooe.2005.09.007","article-title":"Peripheral Brown Tumor of Hyperparathyroidism in the Oral Cavity","volume":"42","author":"Guimar\u00e3es A. 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