{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T05:12:56Z","timestamp":1777957976697,"version":"3.51.4"},"reference-count":11,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Hydatidosis, caused by\n                    <jats:italic>Echinococcus granulosus<\/jats:italic>\n                    , most commonly affects the liver and lungs, while thyroid involvement is exceptionally rare and can mimic other cystic thyroid lesions. We report a 40\u2010year\u2010old woman with no history of animal exposure who presented with anterior neck swelling, odynophagia, and abdominal discomfort. She had a prior history of hepatic hydatid cyst treated in 2018. Thyroid ultrasonography revealed a left subcapsular mass measuring 50\u2009\u00d7\u200938\u2009\u00d7\u200924\u2009mm containing a bilobulated internal cyst (27\u2009\u00d7\u200920\u2009\u00d7\u200910\u2009mm) without significant vascularity. Abdominal imaging demonstrated a large subhepatic multiseptated cyst (115\u2009\u00d7\u200990\u2009\u00d7\u200960\u2009mm) with double\u2010layered septations, suggestive of recurrent hydatidosis. The patient underwent left thyroid lobectomy, and histopathological examination confirmed a hydatid cyst characterized by a laminated membrane and germinal layer, along with surrounding granulation tissue, fibrosis, and multinucleated giant cell reaction in the adjacent thyroid parenchyma. Thyroid hydatid cysts are exceedingly uncommon and may be easily misdiagnosed as other cystic thyroid lesions based on clinical and radiologic findings. Therefore, in endemic regions, hydatid disease should be considered in the differential diagnosis to ensure accurate diagnosis and appropriate management.\n                  <\/jats:p>","DOI":"10.1002\/ccr3.72646","type":"journal-article","created":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T04:35:21Z","timestamp":1777955721000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hydatid Cyst of the Thyroid Gland With Concurrent Hepatic Involvement: A Rare Case Report"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0947-1867","authenticated-orcid":false,"given":"Hana","family":"Saffar","sequence":"first","affiliation":[{"name":"Department of Pathology, Cancer Institute Imam Khomeini Hospital Complex, Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-8862-3008","authenticated-orcid":false,"given":"Aysan","family":"Nozheh","sequence":"additional","affiliation":[{"name":"Department of Pathology, Cancer Institute Imam Khomeini Hospital Complex, Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-5883-8481","authenticated-orcid":false,"given":"Maral","family":"Edalati","sequence":"additional","affiliation":[{"name":"Department of Pathology, Cancer Institute Imam Khomeini Hospital Complex, Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,5,4]]},"reference":[{"issue":"1","key":"e_1_2_12_2_1","doi-asserted-by":"crossref","DOI":"10.1186\/s13256-023-04141-3","article-title":"Primary Hydatid Cyst of the Thyroid Glands: Two Case Reports and a Review of the Literature","volume":"17","author":"Safarpour M. M.","year":"2023","journal-title":"Journal of Medical Case Reports"},{"issue":"1","key":"e_1_2_12_3_1","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1128\/CMR.17.1.107-135.2004","article-title":"Biological, Epidemiological, and Clinical Aspects of Echinococcosis, A Zoonosis of Increasing Concern","volume":"17","author":"Eckert J.","year":"2004","journal-title":"Clinical Microbiology Reviews"},{"issue":"3","key":"e_1_2_12_4_1","doi-asserted-by":"crossref","DOI":"10.5812\/ijem-163775","article-title":"Hydatid Cyst Disease of the Thyroid Gland: A Rare Case Report","volume":"23","author":"Dehghan P.","year":"2025","journal-title":"International Journal of Endocrinology and Metabolism"},{"issue":"4","key":"e_1_2_12_5_1","doi-asserted-by":"crossref","first-page":"643","DOI":"10.9738\/INTSURG-D-14-00124.1","article-title":"Hydatid Cyst Disease of the Thyroid Gland: Report of Two Cases","volume":"100","author":"Akbulut S.","year":"2015","journal-title":"International Surgery"},{"issue":"1","key":"e_1_2_12_6_1","first-page":"2","article-title":"Unusual Locations of the Hydatid Cyst: A Review From Iran","volume":"38","author":"Geramizadeh B.","year":"2013","journal-title":"Iranian Journal of Medical Sciences"},{"issue":"3","key":"e_1_2_12_7_1","article-title":"Hydatid Cysts of the Tongue: A Systematic Review of the Literature","volume":"25","author":"Nawshad Muhammed G. S. O.","year":"2024","journal-title":"Barw Medical Journal"},{"key":"e_1_2_12_8_1","doi-asserted-by":"crossref","DOI":"10.1155\/2011\/713089","article-title":"Primary Hydatid Cyst of the Thyroid Gland","volume":"2011","author":"Azendour I.","year":"2011","journal-title":"International Journal of Otolaryngology"},{"issue":"1","key":"e_1_2_12_9_1","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1186\/s12879-024-09778-z","article-title":"Thyroid Involvement in Cystic Echinococcosis: A Systematic Review","volume":"24","author":"Aledavoud A.","year":"2024","journal-title":"BMC Infectious Diseases"},{"issue":"1","key":"e_1_2_12_10_1","doi-asserted-by":"crossref","DOI":"10.1186\/s13256-024-04807-6","article-title":"Unexpected Discovery of a Thyroid Hydatid Cyst During Pathological Examination: A Case Report","volume":"18","author":"Boujguenna I.","year":"2024","journal-title":"Journal of Medical Case Reports"},{"issue":"4","key":"e_1_2_12_11_1","doi-asserted-by":"crossref","DOI":"10.1002\/ccr3.70337","article-title":"Hydatid Cyst of Thyroid Gland: A Case Report","volume":"13","author":"Ghimire P.","year":"2025","journal-title":"Clinical Case Reports"},{"key":"e_1_2_12_12_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijscr.2023.108355","article-title":"Hydatid Cyst in the Parotid Gland, a Rare Localization of the Disease: A Case Report","volume":"107","author":"Boumediene M.","year":"2023","journal-title":"International Journal of Surgery Case Reports"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.72646","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.72646","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.72646","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T04:35:32Z","timestamp":1777955732000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.72646"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":11,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1002\/ccr3.72646"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.72646","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"2025-12-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e72646"}}