{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T11:09:08Z","timestamp":1778929748402,"version":"3.51.4"},"reference-count":15,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T00:00:00Z","timestamp":1778457600000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Ovarian fibroma with minor sex cord elements is a rare and underrecognized histological variant of ovarian stromal tumors. While the bulk of the tumor resembles a classic fibroma, the presence of small foci of sexcord\u2010like cells can create a diagnostic dilemma, particularly in limited samples. This tumor exhibits hormonal production resulting in endometrial hyperplasia, polyp, or even carcinoma. We report the case of a 56\u2010year\u2010old postmenopausal woman who presented with a history of intermittent postmenopausal bleeding and lower abdominal discomfort with primary infertility. There was a slowly enlarging pelvic mass discovered incidentally on ultrasound imaging. Surgical excision revealed a firm, white encapsulated ovarian tumor. Histologically, the lesion was composed of interlacing bundles of bland spindle cells, characteristic of a fibroma. Notably, scattered discrete clusters and cords of cells resembling Granulosa or Sertoli\u2010type differentiation were observed, occupying less than 10% of the tumor area. These minor sex cord elements exhibited uniform round to oval nuclei and scant cytoplasm, without atypia or mitotic activity. Immunohistochemistry supported the diagnosis, with calretinin and inhibin positivity in the sex cord foci, while the stromal component showed SMA positivity. We report this case because of its rarity and its silent clinical presentation.<\/jats:p>","DOI":"10.1002\/ccr3.72685","type":"journal-article","created":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T10:37:05Z","timestamp":1778495825000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Rare Variant of Ovarian Fibroma With Minor Sex Cord Elements: A Unique Expression of Stromal Differentiation"],"prefix":"10.1002","volume":"14","author":[{"given":"Saira","family":"Rathore","sequence":"first","affiliation":[{"name":"Chughtai Institute of Pathology  Lahore Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanwal","family":"Babar","sequence":"additional","affiliation":[{"name":"Chughtai Institute of Pathology  Lahore Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noreen","family":"Javaid","sequence":"additional","affiliation":[{"name":"Chughtai Institute of Pathology  Lahore Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9046-3003","authenticated-orcid":false,"given":"Aalaa","family":"Saleh","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medical Sciences Lebanese University  Beirut Lebanon"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,5,11]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004347-198303000-00001"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000534798"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13224\u2010015\u20100759\u20109"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.18203\/2320\u20106012.ijrms20201358"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/1757\u20101626\u20101\u2010264"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-3952(22)04460-X"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/1746\u20101596\u20102\u201046"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/1066896917700727"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/IJPM.IJPM_446_17"},{"key":"e_1_2_15_11_1","first-page":"1064","article-title":"Bilateral Ovarian Fibroma With Minor Sex Cord Elements: An Unusual Neoplasm","volume":"6","author":"Gupta N.","year":"2012","journal-title":"Journal of Clinical and Diagnostic Research"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13193\u2010024\u201001951\u20109"},{"key":"e_1_2_15_13_1","doi-asserted-by":"publisher","DOI":"10.4103\/0971\u20105851.113432"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.4081\/pr.2014.5447"},{"issue":"6","key":"e_1_2_15_15_1","first-page":"2114","article-title":"Ovarian Stromal Tumor With Minor Sex Cord Element With Virilizing Manifestations: A Rare Case Report","volume":"4","author":"Sharma R.","year":"2015","journal-title":"International Journal of Reproduction, Contraception, Obstetrics and Gynecology"},{"key":"e_1_2_15_16_1","doi-asserted-by":"publisher","DOI":"10.5858\/2003\u2010127\u201081\u2010FOTOAI"}],"container-title":["Clinical Case 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