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The syndrome is often complicated by infection with intracellular pathogens and viruses, autoimmunity, and inflammation. Hemophagocytic lymphohistiocytosis (HLH) is a rare occurrence that can present further management challenges. Here, we describe a young adult with GATA2 deficiency presenting with\n                    <jats:italic>Legionella<\/jats:italic>\n                    pneumonia, COVID\u201019, and HLH with underlying\n                    <jats:italic>SF3B1<\/jats:italic>\n                    \u2010mutated myelodysplasia that responded successfully to allogeneic hematopoietic stem cell transplantation.\n                  <\/jats:p>","DOI":"10.1002\/ccr3.72699","type":"journal-article","created":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T08:27:31Z","timestamp":1778574451000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hemophagocytic Lymphohistiocytosis Triggered by\n                    <scp>\n                      <i>Legionella pneumophila<\/i>\n                    <\/scp>\n                    and\n                    <scp>SARS<\/scp>\n                    \u2010\n                    <scp>CoV<\/scp>\n                    \u20102 Infection in\n                    <scp>GATA2<\/scp>\n                    Deficiency"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-0038-8877","authenticated-orcid":false,"given":"Harry","family":"Wilson","sequence":"first","affiliation":[{"name":"Haematopoiesis and Immunity Laboratory Newcastle University  Newcastle upon Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nuno","family":"Borges","sequence":"additional","affiliation":[{"name":"Haematopoiesis and Immunity Laboratory Newcastle University  Newcastle upon Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Collin","sequence":"additional","affiliation":[{"name":"Haematopoiesis and Immunity Laboratory Newcastle University  Newcastle upon Tyne UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Callum","family":"Wright","sequence":"additional","affiliation":[{"name":"Haematopoiesis and Immunity Laboratory 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