{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T15:05:47Z","timestamp":1785769547452,"version":"3.56.0"},"reference-count":12,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T00:00:00Z","timestamp":1682294400000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2023,4]]},"abstract":"\n Key Clinical Message<\/jats:title>\n This is an extremely rare case that has not been presented or discussed in the literature to the best of our knowledge. The overlap of connective tissue disease is a challenge for physicians and patients, and it needs special care and regular clinical and laboratory follow\u2010up.<\/jats:p>\n <\/jats:sec>\n \n Abstract<\/jats:title>\n This report describes a rare case of overlapping connective tissue diseases in a 42\u2010year\u2010old female with rheumatoid arthritis, Sjogren's syndrome, antiphospholipid syndrome, and dermatomyositis. The patient presented with a hyperpigmented erythematous rash, muscle weakness, and pain, highlighting the challenges of diagnosis and treatment that require regular clinical and laboratory follow\u2010up.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/ccr3.7274","type":"journal-article","created":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T02:55:40Z","timestamp":1682391340000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["A novel overlap syndrome: Rheumatoid arthritis, Sjogren's syndrome, antiphospholipid syndrome, and dermatomyositis"],"prefix":"10.1002","volume":"11","author":[{"given":"Maab Jasim","family":"Mohammed","sequence":"first","affiliation":[{"name":"Rheumatology Unit, Department of Internal Medicine Al Nu'man Teaching Hospital Baghdad Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6155-7302","authenticated-orcid":false,"given":"Hashim Talib","family":"Hashim","sequence":"additional","affiliation":[{"name":"MBChB, College of Medicine University of Baghdad Baghdad Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7789-1727","authenticated-orcid":false,"given":"Ahmed Dheyaa","family":"Al\u2010Obaidi","sequence":"additional","affiliation":[{"name":"College of Medicine University of Baghdad Baghdad Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Assim","family":"Al\u00a0Shammari","sequence":"additional","affiliation":[{"name":"Respiratory Unit, Department of Internal Medicine Al Yarmouk Teaching Hospital Baghdad Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,4,24]]},"reference":[{"issue":"2","key":"e_1_2_10_2_1","first-page":"136","article-title":"Undifferentiated connective tissue disease, mixed connective tissue disease, and overlap syndromes in rheumatology","volume":"113","author":"Pepmueller PH","year":"2016","journal-title":"Mo Med"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kem021"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.101248"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(199811)41:11<1938::AID-ART7>3.0.CO;2-X"},{"issue":"11","key":"e_1_2_10_6_1","first-page":"2499","article-title":"Determining overlap of systemic lupus erythematosus with rheumatoid arthritis and other connective tissue diseases","volume":"36","author":"Al\u2010Dhaher FF","year":"2009","journal-title":"J Rheumatol"},{"key":"e_1_2_10_7_1","first-page":"41","volume-title":"Mixed Connective Tissue Disease and Anti\u2010Nuclear Antibodies","author":"Kasukawa R","year":"1987"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002281-199112000-00016"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1411863"},{"issue":"1","key":"e_1_2_10_10_1","first-page":"14","article-title":"Scleroderma overlap syndrome","volume":"13","author":"Balbir\u2010Gurman A","year":"2011","journal-title":"Isr Med Assoc J"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2001.22131"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.md.0000173991.74008.b0"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.4081\/cp.2011.e89"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.7274","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T14:01:51Z","timestamp":1764252111000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.7274"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.1002\/ccr3.7274"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.7274","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"2022-11-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e7274"}}