{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T17:05:16Z","timestamp":1784307916902,"version":"3.55.0"},"reference-count":18,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>We present the case of a 78\u2010year\u2010old woman with metabolic syndrome and a history of multiple ischemic strokes who developed progressive symmetrical proximal muscle weakness, predominantly affecting the lower extremities, while on atorvastatin. Laboratory evaluation revealed markedly elevated creatine kinase (CK) and positive anti\u2010HMG\u2010CoA reductase (anti\u2010HMGCR) antibodies, with MRI confirming myositis consistent with statin\u2010induced necrotizing autoimmune myopathy (SINAM). Despite statin discontinuation and immunosuppressive treatment, her muscle weakness persisted, and she remained bedbound at long\u2010term follow\u2010up. This case underscores the diagnostic and therapeutic challenges of SINAM in elderly patients with significant comorbidities and highlights the importance of early recognition and tailored management.<\/jats:p>","DOI":"10.1002\/ccr3.72811","type":"journal-article","created":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T08:14:31Z","timestamp":1779869671000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Diagnostic and Therapeutic Challenges in Statin\u2010Induced Necrotizing Autoimmune Myopathy in an Elderly Patient: A Rare Case Report"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1118-3039","authenticated-orcid":false,"given":"Nischal","family":"Shrestha","sequence":"first","affiliation":[{"name":"Nobel Medical College Teaching Hospital  Biratnagar Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdirahman","family":"Hassan","sequence":"additional","affiliation":[{"name":"MedStar Union Memorial Hospital  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer Ann","family":"Evans","sequence":"additional","affiliation":[{"name":"MedStar Union Memorial Hospital  Baltimore Maryland 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