{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T17:05:53Z","timestamp":1784307953055,"version":"3.55.0"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T00:00:00Z","timestamp":1780617600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>This case report details the integration of nonsurgical endodontic treatment (NSET) and vital pulp therapy (VPT) for symptomatic irreversible pulpitis (SIP) and symptomatic apical periodontitis (SAP) in a mature maxillary molar, with 5\u2010year follow\u2010up. A 23\u2010year\u2010old female presented with sensitivity in tooth #26 due to extensive distal caries. Initial pulpotomy with Five Mineral Oxides (5MO) failed after 1\u2009month, revealing SIP\/SAP. Selective NSET was performed on buccal canals (MB1, MB2, DB), while 5MO preserved vitality in the palatal canal. Buccal canals were obturated; the tooth was restored with amalgam. Annual follow\u2010ups over 60\u2009months showed no symptoms, intact periodontal ligament spaces, and transient sensibility response in the palatal canal on electric pulp testing a flexible treatment plan Selective NSET plus VPT provided long\u2010term clinical and radiographic success in this case, suggesting a conservative, biology\u2010based alternative to full pulpectomy in selected multirooted teeth with localized pathology.<\/jats:p>","DOI":"10.1002\/ccr3.72878","type":"journal-article","created":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T11:22:14Z","timestamp":1780658534000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Five\u2010Year Success of Endodontics Plus Vital Pulp Therapy in a Symptomatic Maxillary Molar: A Case Report"],"prefix":"10.1002","volume":"14","author":[{"given":"Talal","family":"Al\u2010Nahlawi","sequence":"first","affiliation":[{"name":"Department of Operative Dentistry Syrian Private University  Damascus Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8895-3524","authenticated-orcid":false,"given":"Hadi","family":"Assadian","sequence":"additional","affiliation":[{"name":"Department of Endodontics, School of Dentistry Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4195-9202","authenticated-orcid":false,"given":"Ziba","family":"Ghorvei Nossrat","sequence":"additional","affiliation":[{"name":"Department of Endodontics, School of Dentistry Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,5]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2014.08.010"},{"issue":"8","key":"e_1_2_12_3_1","article-title":"Beyond Tradition: Non\u2010Surgical Endodontics and Vital Pulp Therapy as a Dynamic Combination","volume":"15","author":"Urkande N. K.","year":"2023","journal-title":"Cureus"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2020.10.010"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2012.02016.x"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jds.2024.08.002"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781119553939.ch26"},{"issue":"4","key":"e_1_2_12_8_1","article-title":"Pathogenesis of Apical Periodontitis: A Literature Review","volume":"2","author":"Graunaite I.","year":"2012","journal-title":"Journal of Oral & Maxillofacial Research"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2021.09.008"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11144016"},{"issue":"2","key":"e_1_2_12_11_1","first-page":"68","article-title":"Vital Pulp Therapy of Permanent Mature Teeth","volume":"38","author":"Esposito L.","year":"2024","journal-title":"Giornale Italiano di Endodonzia"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-52654-8"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/clinpract13040082"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41432-024-01008-4"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2019.05.022"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/aej.12392"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/2155226"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13872"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-4477.2002.tb00364.x"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2020.06.037"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-62565-3"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.4103\/1735-3327.344163"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/adj.12997"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2012.06.012"}],"container-title":["Clinical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.72878","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccr3.72878","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccr3.72878","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T16:22:24Z","timestamp":1784305344000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccr3.72878"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":23,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1002\/ccr3.72878"],"URL":"https:\/\/doi.org\/10.1002\/ccr3.72878","archive":["Portico"],"relation":{},"ISSN":["2050-0904","2050-0904"],"issn-type":[{"value":"2050-0904","type":"print"},{"value":"2050-0904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"2025-10-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e72878"}}