{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T17:04:38Z","timestamp":1784307878102,"version":"3.55.0"},"reference-count":7,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Case Reports"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Neonatal herpes simplex virus (HSV) infection is an uncommon but potentially devastating condition. Ocular involvement, particularly herpetic keratitis, can cause significant morbidity if not promptly recognized and treated. We present a case of isolated HSV\u20101 keratitis in a 25\u2010day\u2010old neonate successfully managed with intravenous acyclovir; however, the patient subsequently developed HSV encephalitis. This case underscores the importance of considering HSV infection in neonates presenting with ocular symptoms, even in the absence of systemic manifestations, and highlights the risk of late\u2010onset complications.<\/jats:p>","DOI":"10.1002\/ccr3.72894","type":"journal-article","created":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T04:50:44Z","timestamp":1781585444000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Neonatal Herpes Simplex Virus Keratitis: Bitter Lessons from a Case Report"],"prefix":"10.1002","volume":"14","author":[{"given":"Mohammad Saeid","family":"Sasan","sequence":"first","affiliation":[{"name":"Faculty of Medicine Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6490-8961","authenticated-orcid":false,"given":"Amin","family":"Saeidinia","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Mashhad University of Medical Sciences  Mashhad Iran"},{"name":"Booali Research Institute, Pharmacological Research Center Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,15]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.29024"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/9781555815981.ch19"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.32641\/andespediatr.v93i5.4115"},{"issue":"2","key":"e_1_2_14_5_1","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.oftale.2016.01.006","article-title":"Stromal Keratitis in a Neonate: Herpes Virus a Diagnosis to Consider","volume":"91","author":"S\u00e1nchez\u2010Tocino H.","year":"2016","journal-title":"Archivos de la Sociedad Espa\u00f1ola de Oftalmolog\u00eda (English Edition)"},{"key":"e_1_2_14_6_1","volume-title":"Red Book 2021\u20132024: Report of the Committee on Infectious Diseases","author":"Kimberlin D. 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